Protein Alignment AstA-R1 and npr-11

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_508234.2
• Gene: npr-11 / 182921
• WormBaseID: WBGene00016110
• Length: 402
• Species: Caenorhabditis elegans
• Alignment Length: 370
• Identity: 94/370 - (25%)
• Similarity: 153/370 - (41%)
• Gaps: 75/370 - (20%)

  Fly    29 GSIISVSNSSGNNYA--FTSEHTDHSDHNANDSMEYDAESVALERIVSTIVPVFFG-IIGFA--- 87
            ||:    |.|.:||.  |...:....|....:..||.              |..|| .|.||
 Worm     2 GSV----NESCDNYVEIFNKINYFFRDDQVINGTEYS--------------PKEFGYFITFAYML 48

  Fly    88 ----GLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCK 148
                |.:||.|.|:||:.|..||:|.|..|:|||:||....|...|.|....:...|||....||
 Worm    49 IILFGAIGNFLTIIVVILNPAMRTTRNFFILNLALSDFFVCIVTAPTTLYTVLYMFWPFSRTLCK 113

  Fly   149 FVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLA---IMCAWITIVTTAIP-- 208
            ....:.......|.:::..::.||::.::.|.     :.||...|:   .:..|:..:..|:|
 Worm   114 IAGSLQGFNIFLSTFSIASIAVDRYVLIIFPT-----KRERQQNLSFCFFIMIWVISLILAVPLL 173

  Fly   209 ---------VALSHSVRIYQYHGNAGTACVFSTEEEIW-----SLVGFQVSFFLSSYVAPLTLIC 259
                     |..|..:.:|..|          .:.|||     |...:.::..::.|..||..:.
 Worm   174 QASDLTPVFVEPSCDLALYICH----------EQNEIWEKMIISKGTYTLAVLITQYAFPLFSLV 228

  Fly   260 FLYMGMLARLW-------KSAPGCKPSAESRKG----KRRVTRMVVVVVLAFAICWLPIHVILVL 313
            |.|..:..|:.       ::......:::.|:.    :||...::|.||..||:.|||::|..:.
 Worm   229 FAYSRIAHRMKLRFANRNQNVTTNTNTSQRRRSVVERQRRTHLLLVCVVAVFAVAWLPLNVFHIF 293

  Fly   314 KALNLYGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAF 358
            ....|.  :..||....|.|.:|..::|:||::|||.:.|||..|
 Worm   294 NTFELV--NSFSVTTFSICHCLAMCSACLNPLIYAFFNHNFRIEF 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	83/320 (26%)
		TM helix 1	76..102	CDD:320224	13/33 (39%)
		TM helix 2	109..135	CDD:320224	10/25 (40%)
		TM helix 3	147..177	CDD:320224	5/29 (17%)
		TM helix 4	189..209	CDD:320224	5/33 (15%)
		TM helix 5	239..268	CDD:320224	5/28 (18%)
		TM helix 6	284..314	CDD:320224	11/33 (33%)
		TM helix 7	326..351	CDD:320224	10/24 (42%)
npr-11	NP_508234.2	7tmA_NPYR-like	40..336	CDD:320331	80/312 (26%)
		TM helix 1	41..67	CDD:320331	10/25 (40%)
		TM helix 2	74..99	CDD:320331	10/24 (42%)
		TM helix 3	112..142	CDD:320331	5/29 (17%)
		TM helix 4	153..174	CDD:320331	4/20 (20%)
		TM helix 5	208..237	CDD:320331	5/28 (18%)
		TM helix 6	264..294	CDD:320331	11/29 (38%)
		TM helix 7	304..329	CDD:320331	10/24 (42%)