Protein Alignment AstA-R1 and npr-4

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001300304.1
• Gene: npr-4 / 182684
• WormBaseID: WBGene00007635
• Length: 490
• Species: Caenorhabditis elegans
• Alignment Length: 381
• Identity: 94/381 - (24%)
• Similarity: 166/381 - (43%)
• Gaps: 58/381 - (15%)

  Fly    55 NANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVS 119
            |.|..:....|.::....:..:....:.||..||::||..|||.:..|:.:::..||.|::|:.|
 Worm    30 NLNSELWLYREDLSSRWYIMLVFAFLYLIIIAAGIIGNSCVILAITRNKSLQTVPNLFILSLSCS 94

  Fly   120 DILFVIFCVPFTATDYVL--PEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTS 182
            ||  |:.|...|.|....  .||.||...|:...::..::...|.:||..:|.||::.:..|:..
 Worm    95 DI--VVCCTSATITPITAFKKEWIFGEALCRIAPFIAGISLCFSTFTLTAISIDRYILIRFPMRK 157

  Fly   183 MSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACV--FSTEEEIWSLVGFQVS 245
            .....:....:||:||:...:|:  |:....  ::.::....|..|.  :...|....:.|..:.
 Worm   158 PITHYQAVGVIAIICAFAATITS--PIMFKQ--KLGEFENFCGQYCTENWGANESQRKIYGAALM 218

  Fly   246 FFLSSYVAPLTLICFLYMGMLARLWKS--APGCKP----------SAESR---KGKRRVTRMVVV 295
            |.  ..|.|||:|...|..:..::.:|  ..|.|.          |.:.|   |.::|..||::.
 Worm   219 FL--QLVIPLTIIIISYTAISLKIGQSMILKGAKKQKTDNWEMELSDQQRIAVKRRQRTNRMLIG 281

  Fly   296 VVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQ-------IISHVVAYTNSCINPILYAFLSDN 353
            :|:|||..|:......:|:..     .:|..:|:       |.:|.:|.|::..||:|||.|:..
 Worm   282 MVVAFACSWIWSVTFNILRDY-----EYLPELIKTQEYIFGIATHCIAMTSTVWNPLLYAVLNLQ 341

  Fly   354 FRKAFRKVV--W---------------CGSPPPLMTNQQVTKTTRT--ATGNGTSN 390
            .|.||..::  |               ...|...:||:..:..|:|  ||...|||
 Worm   342 LRAAFIDLMPHWLRRHLNLEGDNSSPLLNHPTMTITNKYGSTATKTVKATYINTSN 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	78/308 (25%)
		TM helix 1	76..102	CDD:320224	9/25 (36%)
		TM helix 2	109..135	CDD:320224	11/25 (44%)
		TM helix 3	147..177	CDD:320224	7/29 (24%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	8/28 (29%)
		TM helix 6	284..314	CDD:320224	9/29 (31%)
		TM helix 7	326..351	CDD:320224	10/31 (32%)
npr-4	NP_001300304.1	7tmA_NPYR-like	50..346	CDD:320331	78/308 (25%)
		TM helix 1	51..77	CDD:320331	9/25 (36%)
		TM helix 2	84..109	CDD:320331	11/26 (42%)
		TM helix 3	122..152	CDD:320331	7/29 (24%)
		TM helix 4	163..184	CDD:320331	6/22 (27%)
		TM helix 5	210..239	CDD:320331	8/30 (27%)
		TM helix 6	270..300	CDD:320331	9/29 (31%)
		TM helix 7	314..339	CDD:320331	9/24 (38%)