Protein Alignment AstA-R1 and npr-28

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_509416.2
• Gene: npr-28 / 181089
• WormBaseID: WBGene00018886
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 444
• Identity: 105/444 - (23%)
• Similarity: 177/444 - (39%)
• Gaps: 133/444 - (29%)

  Fly    30 SIISVSNSSGNNYAFTSEHTDHSD---HNANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLLG 91
            |.:::|::|    ..|:..|..|.   .:.||.||...|.:        .|.|.:..:...|:.|
 Worm     2 STMTISSTS----ILTTVSTTTSSTIVPSLNDPMEIQFEIM--------FVMVLYSCLAVTGVGG 54

  Fly    92 NGLVILVVV-------ANQQ------MRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFG 143
            |..|::.|:       :|:.      ::|:..:.:|.|:|.| ||.:..||...||..:..:|||
 Worm    55 NCWVLIKVIKQLSGCSSNRSRPYKTVVQSSAYVYLIILSVVD-LFSLIPVPMIVTDVYVNHFPFG 118

  Fly   144 NVW-CKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNA--TLAIMCAWITIVTT 205
             :| ||...:...:....|...|..:|.||::||.|| |...|||.:.:  .||: |..:::: .
 Worm   119 -LWACKLSYFCEAINKSLSPMVLTALSVDRYIAVCHP-TLYWLRTTKFSLGVLAV-CFSVSLI-F 179

  Fly   206 AIPVALSHSVRIYQ------------YHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLI 258
            .|||....::::.:            .||:: .:.||.|.:.|            ..|:.||.:|
 Worm   180 IIPVTKKATMQVMKDNTDEEIIKCAFDHGDS-ASYVFDTAQAI------------VCYLVPLFII 231

  Fly   259 CFLYMGMLARLW----KSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLP-----IHVILVLK 314
            |.:|:.:|.:|:    .|..|.|.|.    ...||.:..|:||..:.|||.|     || .||.:
 Worm   232 CAVYLAILHKLFIHTRFSTVGKKTSI----SLGRVVKCSVMVVAFYFICWTPYWTMRIH-YLVTR 291

  Fly   315 ALNLYGGSHLSVIIQIIS-----------------------------------HVVAYTNSCINP 344
            .:......:.:||.::::                                   |.:.|..|..|.
 Worm   292 FIETNSDGNSTVIDEVVAAVAEEVQDGIETSYFFGLISKKRMHNIEIALIYILHSLTYAQSAFNW 356

  Fly   345 ILYAFLSDNFRKAFRKVVWCGSPPPLMTNQQVTKTTRTA-------TGNGTSNI 391
            :.|:||:.|.|                :|......||:|       .||.||.:
 Worm   357 LFYSFLNRNLR----------------SNNGRGNGTRSAANTSVFDNGNATSTV 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	86/354 (24%)
		TM helix 1	76..102	CDD:320224	7/32 (22%)
		TM helix 2	109..135	CDD:320224	9/25 (36%)
		TM helix 3	147..177	CDD:320224	8/29 (28%)
		TM helix 4	189..209	CDD:320224	4/21 (19%)
		TM helix 5	239..268	CDD:320224	7/28 (25%)
		TM helix 6	284..314	CDD:320224	13/34 (38%)
		TM helix 7	326..351	CDD:320224	8/59 (14%)
npr-28	NP_509416.2	7tm_classA_rhodopsin-like	41..363	CDD:410626	82/344 (24%)
		TM helix 1	41..72	CDD:410626	6/30 (20%)
		TM helix 2	85..110	CDD:410626	9/25 (36%)
		TM helix 3	122..152	CDD:410626	8/29 (28%)
		TM helix 4	164..183	CDD:410626	4/20 (20%)
		TM helix 5	212..237	CDD:410626	10/36 (28%)
		TM helix 6	257..287	CDD:410626	11/34 (32%)
		TM helix 7	338..363	CDD:410626	6/24 (25%)