Protein Alignment AstA-R1 and tyra-2

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001033537.1
• Gene: tyra-2 / 180970
• WormBaseID: WBGene00017157
• Length: 468
• Species: Caenorhabditis elegans
• Alignment Length: 449
• Identity: 77/449 - (17%)
• Similarity: 145/449 - (32%)
• Gaps: 173/449 - (38%)

  Fly    89 LLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYM 153
            :..|.||.:|:..|.::::..|||:.|||.||:...:..:|.::...:..||.|.:..|:.....
 Worm    33 IFANSLVFIVLYKNPRLQTVPNLLVGNLAFSDLALGLIVLPLSSVYAIAGEWVFPDALCEVFVSA 97

  Fly   154 IVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVAL-----SH 213
            .::....|::.|.::..||:.|:..||..||.|.:|.|.:.|:..||:....::...|     :.
 Worm    98 DILCSTASIWNLSIVGLDRYWAITSPVAYMSKRNKRTAGIMILSVWISSALISLAPLLGWKQTAQ 162

  Fly   214 SVRIYQYHGNAGTACVF--STEEEIWSLVGFQVSFFLS--------------------------- 249
            :..:.....|....|.|  .....::|..|   |||:.
 Worm   163 TPNLIYEKNNTVRQCTFLDLPSYTVYSATG---SFFIPTLLMFFVYFKIYQAFAKHRARQIYRQK 224

  Fly   250 --------------------SYVAP---------------------------------------- 254
                                |:|.|
 Worm   225 LAVSSHVIRKHIESTILHEISHVLPTSDEFAKEEEEEEDSESSGQVENGLGNGNDAIIEEDECED 289

  Fly   255 ------------LTLICFL--------YMGMLARLWKSAP------------------------- 274
                        :|.:...        ||...|::.||.|
 Worm   290 EDSDEKRDDHTSMTTVTATVTGPTEAPYMKREAKISKSVPIEKESAIQKREAKPMRSVMAISYEK 354

  Fly   275 ----------------GCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKAL--NLYGG 321
                            ..||.|.|...:||..:::.:::..|.:||.|...:.||...  :....
 Worm   355 VKRHKNRKERIYRKSLQRKPKAISAAKERRGVKVLGIILGCFTVCWAPFFTMYVLVQFCKDCSPN 419

  Fly   322 SHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPPPLMTNQQVTKTT 380
            :|:.:.|..:    .|:||.:|||:|...:.:::.|.::         |.|:::...:|
 Worm   420 AHIEMFITWL----GYSNSAMNPIIYTVFNRDYQIALKR---------LFTSEKKPSST 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	73/425 (17%)
		TM helix 1	76..102	CDD:320224	4/12 (33%)
		TM helix 2	109..135	CDD:320224	9/25 (36%)
		TM helix 3	147..177	CDD:320224	6/29 (21%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	10/135 (7%)
		TM helix 6	284..314	CDD:320224	7/29 (24%)
		TM helix 7	326..351	CDD:320224	8/24 (33%)
tyra-2	NP_001033537.1	7tmA_amine_R-like	20..452	CDD:320098	73/425 (17%)
		TM helix 1	20..46	CDD:320098	4/12 (33%)
		TM helix 2	53..80	CDD:320098	9/26 (35%)
		TM helix 3	91..121	CDD:320098	6/29 (21%)
		TM helix 4	133..153	CDD:320098	5/19 (26%)
		TM helix 5	182..379	CDD:320098	18/199 (9%)
		TM helix 6	380..410	CDD:320098	7/29 (24%)
		TM helix 7	420..445	CDD:320098	9/28 (32%)