Protein Alignment AstA-R1 and npr-1

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_508816.1
• Gene: npr-1 / 180752
• WormBaseID: WBGene00003807
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 344
• Identity: 91/344 - (26%)
• Similarity: 152/344 - (44%)
• Gaps: 57/344 - (16%)

  Fly    62 YDAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIF 126
            |...|.::..||..:....|  :.|.||.||..:|.|..:::.:.|..|:.|:|||.||.:..|.
 Worm    16 YPDPSQSIYAIVPFLTVYLF--LFFLGLFGNVTLIYVTCSHKALLSVQNIFILNLAASDCMMCIL 78

  Fly   127 CVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHP-VTSMSLRTERN 190
            .:|.|....|...|.|||:.|..:..:..::.....::|..::.||::.||.| .|.:|   :|.
 Worm    79 SLPITPITNVYKNWYFGNLLCHLIPCIQGISIFVCTFSLGAIALDRYILVVRPHSTPLS---QRG 140

  Fly   191 ATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTE--EEIWSLVGFQVSFFLSSYVA 253
            |.|..:..||......:|.|.:..:..|......|..|   ||  |...|...:.:...|:.:|.
 Worm   141 AFLTTVLLWILSFVVTLPYAFNMQMIEYTEERICGYFC---TEKWESAKSRRAYTMIVMLAQFVV 202

  Fly   254 PLTLICFLYMGMLARLWKSA---------------PGCK-PS----------------AESRKGK 286
            |..::.|.|..:::.|.|.|               ..|. ||                .|..|.:
 Worm   203 PFAVMAFCYANIVSVLSKRAQTKIRKMVERTSALESSCAFPSHGLEQYENELNEFLDKQEKEKQR 267

  Fly   287 -----RRVTRMVVVVVLAFAICWLPIHVILVL-------KALNLYGGS--HLSVIIQIISHVVAY 337
                 ||.|.::|.:|:.|.|.|||.:||.::       ....|||..  .:|.::.:.:|.:|.
 Worm   268 VVLQNRRTTSILVTMVVWFGITWLPHNVISLIIEYDDTQSFFRLYGRDDYDISYLLNLFTHSIAM 332

  Fly   338 TNSCINPILYAFLSDNFRK 356
            :|:.:||:|||:|:.:||:
 Worm   333 SNNVLNPVLYAWLNPSFRQ 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	87/331 (26%)
		TM helix 1	76..102	CDD:320224	8/25 (32%)
		TM helix 2	109..135	CDD:320224	10/25 (40%)
		TM helix 3	147..177	CDD:320224	4/29 (14%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	5/28 (18%)
		TM helix 6	284..314	CDD:320224	13/41 (32%)
		TM helix 7	326..351	CDD:320224	8/24 (33%)
npr-1	NP_508816.1	7tmA_NPYR-like	27..351	CDD:320331	87/331 (26%)
		TM helix 1	28..54	CDD:320331	8/27 (30%)
		TM helix 2	61..86	CDD:320331	10/24 (42%)
		TM helix 3	99..129	CDD:320331	4/29 (14%)
		TM helix 4	140..161	CDD:320331	5/20 (25%)
		TM helix 5	188..217	CDD:320331	5/28 (18%)
		TM helix 6	270..300	CDD:320331	12/29 (41%)
		TM helix 7	321..346	CDD:320331	8/24 (33%)