Protein Alignment AstA-R1 and npr-16

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001355490.1
• Gene: npr-16 / 180643
• WormBaseID: WBGene00006864
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 372
• Identity: 95/372 - (25%)
• Similarity: 161/372 - (43%)
• Gaps: 49/372 - (13%)

  Fly    51 HSDHNANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIIN 115
            :|.|..:||.::       .|:..|:..:....:|...|    ::||:::....:||.||:.:|.
 Worm     6 YSKHAMSDSSQH-------LRLALTVTHLLLVALGSVNL----IIILLIITRPYLRSITNVYMIG 59

  Fly   116 LAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPV 180
            |.::|.:::...:...||......||||...|...........:.||..:||::.||::|:....
 Worm    60 LCLADFIYLADLILVAATSLNGKSWPFGPTICHLFHGTEATGKYASVLFVVLLAADRYIAMCKSD 124

  Fly   181 TSMSLRTERNATLAIMCAWITIVTTAIPV---ALSHSVRIYQYHG-----NAGTACVF---STEE 234
            .....||.|.|......|||.....::|:   |....||:...:|     |..|.|:.   |...
 Worm   125 LCGRYRTYRTAIFLSGLAWIAAFICSLPLYVYADEIKVRMRPKNGTDSIENNHTLCIAHWPSPPH 189

  Fly   235 EIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCK---PSAESRKGKRRVTRMVVVV 296
            ..|.:....|..|    :.|..:|.:.|..:..:|.::|.|.:   .:..||...:||||.|..|
 Worm   190 AQWYISVCSVMIF----ILPGLVIFYCYYHVFCKLREAAKGSRRLHRNKRSRSSYQRVTRSVQRV 250

  Fly   297 VLAFAICWLPIHVILVLKALNLYGG-------SHLSVIIQIISHVVAYTNSCINPILYAFLSDNF 354
            ||...:||.|..:      .||:..       :.|..||..|.|:..|.|..:||:|||:.::||
 Worm   251 VLFHLLCWSPFWL------FNLFSAIFRVRITTQLMRIIVNIIHLFPYVNCALNPVLYAYRAENF 309

  Fly   355 RKAFRKVVWCGSPP-------PLMTNQQVTKTTRTATGNGTSNIEML 394
            |.||:.:::.....       ||...:.|..|:.:.....:||::.|
 Worm   310 RTAFKSLLFWSRRSVSSKLNRPLPLPEDVRSTSASTYYRNSSNLDCL 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	81/303 (27%)
		TM helix 1	76..102	CDD:320224	4/25 (16%)
		TM helix 2	109..135	CDD:320224	7/25 (28%)
		TM helix 3	147..177	CDD:320224	8/29 (28%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	5/28 (18%)
		TM helix 6	284..314	CDD:320224	11/29 (38%)
		TM helix 7	326..351	CDD:320224	11/24 (46%)
npr-16	NP_001355490.1	7tm_classA_rhodopsin-like	45..305	CDD:410626	73/269 (27%)
		TM helix 2	53..79	CDD:410626	7/25 (28%)
		TM helix 3	91..121	CDD:410626	8/29 (28%)
		TM helix 4	134..153	CDD:410626	4/18 (22%)
		TM helix 5	190..215	CDD:410626	6/28 (21%)
		TM helix 6	238..268	CDD:410626	13/35 (37%)
		TM helix 7	281..305	CDD:410626	11/23 (48%)