Protein Alignment AstA-R1 and npr-2

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_501701.2
• Gene: npr-2 / 177790
• WormBaseID: WBGene00003808
• Length: 430
• Species: Caenorhabditis elegans
• Alignment Length: 410
• Identity: 85/410 - (20%)
• Similarity: 162/410 - (39%)
• Gaps: 85/410 - (20%)

  Fly    51 HSDHNANDSMEYDAESVALERIVS---------TIVPVF---FGIIGFAGLLGNGLVILVVVANQ 103
            ||....|::.|      ..:|.:.         |::..|   :..|...|:|||..|:.:.:.::
 Worm    40 HSSQMINETEE------TCDRYIDKHPDMTNEPTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHR 98

  Fly   104 QMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLM 168
            |:::..|:.|:||..|::|..:..:|.|....|..:|.|.:..||.:..:...:...|.::|..:
 Worm    99 QLQTVQNIFILNLCASNVLMCLTSLPITFITNVYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAI 163

  Fly   169 SFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTE 233
            :.||:..||.|  .....:.|:|.:..:..|:..|...:|......|.  :.:|..|..|
 Worm   164 ALDRYNLVVRP--HKQKLSSRSAMMIALLIWVISVVVCMPYGWYMDVE--KLNGLCGEYC----- 219

  Fly   234 EEIWSLV----GFQVSFFLSSYVAPLTLICFLYMGMLARLWK----------------------- 271
            .|.|.|.    |:.....::.::.|...:.|.|..:.:||.:
 Worm   220 SEHWPLAEVRKGYTFLVLITQFLFPFATMAFCYYNIFSRLRQRVETKLKKLSERSQLLENSTTCG 284

  Fly   272 --------SAPGCKPSAESRK------GKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGG- 321
                    :|...:...|:::      .:||.|.::..:||.||..|||.:|:.::..   |.|
 Worm   285 TTNHIVSINAEAVQNGLENKQRLAVLAQQRRTTTILSCMVLLFAFTWLPHNVVTLMIE---YDGF 346

  Fly   322 ------------SHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPPPLMTNQ 374
                        .| :.|:.:.:|:::...:..||.|||:|:..|::...|.:..||..|...:.
 Worm   347 FFHSDETSATSTDH-TYIVSMTAHLISMLTNVTNPFLYAWLNPMFKEMLIKTLRGGSKSPKPADI 410

  Fly   375 QVTKTTRTATGNGTSNIEML 394
            :.|...|.......|....|
 Worm   411 KQTSFIRMPNSGAPSQSSYL 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	72/339 (21%)
		TM helix 1	76..102	CDD:320224	7/28 (25%)
		TM helix 2	109..135	CDD:320224	8/25 (32%)
		TM helix 3	147..177	CDD:320224	6/29 (21%)
		TM helix 4	189..209	CDD:320224	4/19 (21%)
		TM helix 5	239..268	CDD:320224	5/32 (16%)
		TM helix 6	284..314	CDD:320224	11/35 (31%)
		TM helix 7	326..351	CDD:320224	7/24 (29%)
npr-2	NP_501701.2	7tmA_NPYR-like	70..394	CDD:320331	71/336 (21%)
		TM helix 1	71..97	CDD:320331	7/25 (28%)
		TM helix 2	104..129	CDD:320331	8/24 (33%)
		TM helix 3	142..172	CDD:320331	6/29 (21%)
		TM helix 4	183..204	CDD:320331	4/20 (20%)
		TM helix 5	229..258	CDD:320331	4/28 (14%)
		TM helix 6	311..341	CDD:320331	11/29 (38%)
		TM helix 7	362..387	CDD:320331	7/24 (29%)