Protein Alignment AstA-R1 and tkr-3

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001343603.1
• Gene: tkr-3 / 177285
• WormBaseID: WBGene00006428
• Length: 400
• Species: Caenorhabditis elegans
• Alignment Length: 316
• Identity: 76/316 - (24%)
• Similarity: 147/316 - (46%)
• Gaps: 42/316 - (13%)

  Fly    79 VFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFG 143
            :.:.||.|..::||.||:.:.:...::||.|...|:||..:|:...||.:||.....:..||...
 Worm    51 MLYAIIAFMAVVGNLLVLYITLFRLRVRSITTYFILNLGFADLFTGIFAIPFKFQAALFQEWFLP 115

  Fly   144 NVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSM-----SLRTERNATLAIMCAWITIV 203
            ...|:.|.|:..|....||:|||       .:.||...:|     |..:.|:|...::..||..|
 Worm   116 RSLCRIVPYVETVALTVSVFTLV-------TSAVHEFRTMFFSKCSQMSPRSAKRCVLLIWIMAV 173

  Fly   204 TTAIPVALSHSVRIYQYHGNAGTA---CVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGM 265
            ..::|..|.|:.  |::..:..|:   |:....:..|... :.|...:..|..|:.::...|..:
 Worm   174 LVSLPHGLFHNT--YEFPDDNNTSIVQCLPVYPDAGWWKT-YNVYLVIIQYFVPMIILDTAYTMI 235

  Fly   266 LARLWKSAPGCKPSAESRKGKRRVT---------------RMVVVVVLAFAICWLPIHVILVLKA 315
            ..::|..:.......|::...::::               |.:::||..|::||.|:...|:|..
 Worm   236 AVKIWSLSQSRVELDETKMATQKISVVSMVSPNTQLSQLMRTLIIVVACFSLCWFPLETYLLLNE 300

  Fly   316 L--NLYGGSHLSVIIQIISHVVAYTNSCINPILYAF----LSDNFRKAFRKV--VW 363
            |  .:.|..:::::. ..||.:|.:|||:|||:|..    .::.:|:.||::  :|
 Worm   301 LKPEINGWKYINLVF-FFSHWLAMSNSCLNPIIYGLYNTKYNEEYRRLFRQIGCIW 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	73/307 (24%)
		TM helix 1	76..102	CDD:320224	7/22 (32%)
		TM helix 2	109..135	CDD:320224	9/25 (36%)
		TM helix 3	147..177	CDD:320224	9/29 (31%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	4/28 (14%)
		TM helix 6	284..314	CDD:320224	8/44 (18%)
		TM helix 7	326..351	CDD:320224	10/28 (36%)
tkr-3	NP_001343603.1	7tm_GPCRs	47..344	CDD:475119	72/303 (24%)
		TM helix 1	49..73	CDD:320515	7/21 (33%)
		TM helix 2	82..104	CDD:320515	8/21 (38%)
		TM helix 3	120..142	CDD:320515	8/28 (29%)
		TM helix 4	163..179	CDD:320515	3/15 (20%)
		TM helix 5	210..233	CDD:320515	3/23 (13%)
		TM helix 6	275..297	CDD:320515	7/21 (33%)
		TM helix 7	312..337	CDD:320515	10/25 (40%)