Protein Alignment AstA-R1 and ckr-2

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_001367973.1
• Gene: ckr-2 / 175341
• WormBaseID: WBGene00021439
• Length: 603
• Species: Caenorhabditis elegans
• Alignment Length: 451
• Identity: 96/451 - (21%)
• Similarity: 153/451 - (33%)
• Gaps: 173/451 - (38%)

  Fly    75 TIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPE 139
            ||...|| :|....::||.:|::|::..:.|||.||:.::|||.||::..:.|:|.|....|:..
 Worm    62 TIAVTFF-MIFLLSVVGNSVVLIVIIKQRAMRSITNIYLMNLAASDMMLSVVCMPPTLVSMVMNC 125

  Fly   140 WPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVT 204
            |.|||..||.:.|:..|....|.|||.:::|:|:.|:..|:.|...:|..:|...|...|:..:.
 Worm   126 WMFGNYMCKILAYLQPVVVTASAYTLAVIAFERYFAICKPLHSRIWQTRSHAYAMITLVWVIAIA 190

  Fly   205 TAIPVALSHSVRIYQ-------------YH-----------------------GNAGTACVFSTE 233
            ..|.:...:..:.|.             ||                       ||..|:.....:
 Worm   191 ANILMLFMYEQQTYSSNGYTCAPIHPPIYHFAYQVYMTVVLLVIPLVVMAGLYGNVITSLKSGIK 255

  Fly   234 EEIWS------------------------------LVGFQVSFFLSSYVAPLTLICFLYMGMLAR 268
            .||.|                              |||.......:|.:|..|..|.......:.
 Worm   256 LEIASVDPPLATATTTGAKNLGSHSDSAHLLLNNVLVGSSQLARATSCIALNTFSCNNTTNPFST 320

  Fly   269 LWKSAP------------------------------GCK-------------------------- 277
            |....|                              .|:
 Worm   321 LTPPPPIQQKNRSKPQLLQLPGKIDNFEEFRLQCLSDCRSDGVLFPPPAIVASMTDEQKLSFWNK 385

  Fly   278 --------------------------------PS------AESRKGKRRVTRMVVVVVLAFAICW 304
                                            ||      .:|...|:||.:|::|||:.|..||
 Worm   386 LSNKLTFSQQDKTVQHPNFGHRKSDTSICLENPSLRSTHTQKSAMAKQRVIKMLIVVVIIFFCCW 450

  Fly   305 LPIHVILVL-------KALNL-YGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKA 357
            .|.::..:|       ::||| ...|.::..|.:::    |.:||.|||.|.||:..||.|
 Worm   451 TPSYIWWLLLIAGDSFQSLNLSVWNSDINTFITLLT----YISSCTNPITYCFLNKKFRNA 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	96/451 (21%)
		TM helix 1	76..102	CDD:320224	8/25 (32%)
		TM helix 2	109..135	CDD:320224	10/25 (40%)
		TM helix 3	147..177	CDD:320224	11/29 (38%)
		TM helix 4	189..209	CDD:320224	4/19 (21%)
		TM helix 5	239..268	CDD:320224	7/28 (25%)
		TM helix 6	284..314	CDD:320224	12/36 (33%)
		TM helix 7	326..351	CDD:320224	9/24 (38%)
ckr-2	NP_001367973.1	7tmA_CCKR-like	61..508	CDD:320124	96/451 (21%)
		TM helix 1	62..88	CDD:320124	9/26 (35%)
		TM helix 2	95..121	CDD:320124	10/25 (40%)
		TM helix 3	133..163	CDD:320124	11/29 (38%)
		TM helix 4	177..195	CDD:320124	4/17 (24%)
		TM helix 5	220..245	CDD:320124	1/24 (4%)
		TM helix 6	430..460	CDD:320124	11/29 (38%)
		TM helix 7	476..501	CDD:320124	10/28 (36%)