Protein Alignment AstA-R1 and Grpr

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_032203.1
• Gene: Grpr / 14829
• MGIID: 95836
• Length: 384
• Species: Mus musculus
• Alignment Length: 336
• Identity: 97/336 - (28%)
• Similarity: 158/336 - (47%)
• Gaps: 33/336 - (9%)

  Fly    76 IVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEW 140
            ::|..:|:|...||:||..:|.:....:.||:..||.|.:||:.|:|.::.|.|..|:.|:...|
Mouse    43 VIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRW 107

  Fly   141 PFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTT 205
            .||.:.||.:.::.:.:...||:||..:|.||:.|:|.|:...:........|.....||..:..
Mouse   108 LFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLL 172

  Fly   206 AIPVALSHSVRIYQYHGNAGTACVFSTEEEIWSLVGF-----------QVSFFLSSYVAPLTLIC 259
            |||.|:...  ::.:|       |..|.:...|...:           .::.||..||.||.:|.
Mouse   173 AIPEAVFSD--LHPFH-------VKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLAIIS 228

  Fly   260 FLYMGMLARLWKSAPG--------CKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKAL 316
            ..|..:...|.:||..        .|...||||   |:.:.|:|.|..||.||||.|||.:.::.
Mouse   229 VYYYFIARNLIQSAYNLPVEGNIHVKKQIESRK---RLAKTVLVFVGLFAFCWLPNHVIYLYRSY 290

  Fly   317 NL--YGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPPPLMTNQQVTKT 379
            :.  ...|.|..:..|.:.::|:||||:||.....||.:|||.|...:.|..|..:..:....::
Mouse   291 HYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLMNRSHSTGRS 355

  Fly   380 TRTATGNGTSN 390
            |...|...::|
Mouse   356 TTCMTSFKSTN 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	91/302 (30%)
		TM helix 1	76..102	CDD:320224	8/25 (32%)
		TM helix 2	109..135	CDD:320224	10/25 (40%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	8/39 (21%)
		TM helix 6	284..314	CDD:320224	14/29 (48%)
		TM helix 7	326..351	CDD:320224	8/24 (33%)
Grpr	NP_032203.1	7tmA_GRPR	42..334	CDD:320252	91/302 (30%)
		TM helix 1	43..69	CDD:320252	8/25 (32%)
		TM helix 2	76..102	CDD:320252	10/25 (40%)
		TM helix 3	114..144	CDD:320252	10/29 (34%)
		TM helix 4	156..176	CDD:320252	5/19 (26%)
		TM helix 5	208..233	CDD:320252	8/24 (33%)
		TM helix 6	258..288	CDD:320252	17/32 (53%)
		TM helix 7	302..327	CDD:320252	8/24 (33%)