Protein Alignment AstA-R1 and Ackr2

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_511176.2
• Gene: Ackr2 / 140473
• RGDID: 620323
• Length: 382
• Species: Rattus norvegicus
• Alignment Length: 373
• Identity: 102/373 - (27%)
• Similarity: 173/373 - (46%)
• Gaps: 67/373 - (17%)

  Fly    11 LATLISSWPKASWGATGNGSIISVSNSSGNNYAFTSEHT------DHSDHNANDSMEYDAESVAL 69
            :.|:.|..|.|:.|.....||.        :|.:..:.|      |              |.::.
  Rat     1 MPTIASPLPLATTGPENGSSIY--------DYDYLDDVTVLVCSKD--------------EVLSF 43

  Fly    70 ERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQ--QMRSTTNLLIINLAVSDILFVIFCVPFTA 132
            .|:   .:||.:.:|...||.|| |::|||:.:.  |.|....|.::|||||::|||: .:||.|
  Rat    44 GRV---FLPVVYSLIFVLGLAGN-LLLLVVLLHSVPQRRRMIELYLLNLAVSNLLFVV-TMPFWA 103

  Fly   133 TDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMC 197
            .. |...|.||:..||.|..:..:..:|.::.:..||.|::|.:||.......:|.....|.|:.
  Rat   104 IS-VAWHWVFGSFLCKVVSTLYSINFYCGIFFITCMSLDKYLEIVHAQPLHRPKTRFRNLLLIVM 167

  Fly   198 AWITIVTTAIPVALSHSVRIYQ-----YHGNAGTACVFSTEEEIWSL-VGFQVSFFLSSYVAPLT 256
            .|||.:..::|..:  .|:::|     :|..|.    |.....||.| :.||::  |..::.||.
  Rat   168 VWITALAVSVPEMV--FVKVHQTLDGVWHCYAD----FGGHATIWKLYLRFQMN--LLGFLFPLL 224

  Fly   257 LICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKA---LNL 318
            .:.|.|         |..||........|:.|..|....:|:.|.:.|.|.::.|.|.:   |::
  Rat   225 AMIFFY---------SRIGCVLVRLRPPGQGRALRTAAALVVVFFLLWFPYNLTLFLHSLLDLHV 280

  Fly   319 YGG---SH-LSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVV 362
            :|.   || |..::| ::..:|:::.|..|:||||.|.:||:..:.|:
  Rat   281 FGNCEISHRLDYMLQ-VTESLAFSHCCFTPVLYAFSSHSFRQYLKAVL 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	89/297 (30%)
		TM helix 1	76..102	CDD:320224	11/25 (44%)
		TM helix 2	109..135	CDD:320224	12/25 (48%)
		TM helix 3	147..177	CDD:320224	8/29 (28%)
		TM helix 4	189..209	CDD:320224	5/19 (26%)
		TM helix 5	239..268	CDD:320224	8/29 (28%)
		TM helix 6	284..314	CDD:320224	8/29 (28%)
		TM helix 7	326..351	CDD:320224	8/24 (33%)
Ackr2	NP_511176.2	7tmA_ACKR2_D6	46..323	CDD:320316	89/300 (30%)
		TM helix 1	46..73	CDD:320316	11/30 (37%)
		TM helix 2	81..106	CDD:320316	12/26 (46%)
		TM helix 3	117..147	CDD:320316	8/29 (28%)
		TM helix 4	159..181	CDD:320316	6/21 (29%)
		TM helix 5	207..236	CDD:320316	10/39 (26%)
		TM helix 6	243..273	CDD:320316	8/29 (28%)
		TM helix 7	291..316	CDD:320316	8/25 (32%)
		C-terminal cytoplasmic tail. /evidence=ECO:0000250	327..382		0/1 (0%)