Protein Alignment AstA-R1 and sNPF-R

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: XP_320180.2
• Gene: sNPF-R / 1280335
• VectorBaseID: AGAMI1_013226
• Length: 575
• Species: Anopheles gambiae
• Alignment Length: 356
• Identity: 104/356 - (29%)
• Similarity: 165/356 - (46%)
• Gaps: 38/356 - (10%)

  Fly    37 SSGNNYAFTSEHTDHSDHNANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVA 101
            |:..|...|.|.....:.:.......|.:.:...::|..:..|.:..|...|:.||.||..||..
Mosquito    58 SNATNLTLTLEELLRPNSSTVAPPNGDNDIIFSNKLVQIVFCVLYSSIFVLGVFGNVLVCYVVFR 122

  Fly   102 NQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVY--- 163
            |:.|::.|||.|.|||:||||..:..||||.:...:..|.||.:.|    :.:.:...||||
Mosquito   123 NKAMQTVTNLFITNLALSDILLCVLAVPFTPSYTFMRRWVFGKLLC----HTVPLAQGCSVYIST 183

  Fly   164 -TLVLMSFDRFLAVVHPV-TSMSLRTERNATLAIMCAWITIVTTAIPVAL---SHSVRIYQYHGN 223
             ||..::.|||..:::|. ..|.|.|   ....|:..|...:...:|..|   .|.|.:......
Mosquito   184 LTLTSIAIDRFFVIIYPFHPRMKLST---CITIIVLIWSFAIMVTMPYGLYMKLHGVALNGTDNA 245

  Fly   224 AGTACVFSTEEEIWSLVGFQVSFFLSS----YVAPLTLICFLYMGMLARL---WKSAPGCKPSAE 281
            .|........||:|.....:.:|.:.:    :|.|..::.|.|:.:..||   .::.||.|.|..
Mosquito   246 TGPLSSAMYCEELWPSEEMRKTFSIVTSILQFVLPFIIMAFCYICVSIRLNDRARTKPGSKTSRR 310

  Fly   282 ---SRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALN-------LYGGSHLSVIIQIISHVVA 336
               .|..|:|..||::.:|..|.|.|||::|:.:....|       .|.      :|..|:|:.|
Mosquito   311 EEADRDRKKRTNRMLISMVAIFGISWLPLNVVNMCNDFNSDINSWRFYN------LIFFIAHLTA 369

  Fly   337 YTNSCINPILYAFLSDNFRKAFRKVVWCGSP 367
            .:::|.||.|||:|:|||||.|::|:.|..|
Mosquito   370 MSSTCYNPFLYAWLNDNFRKEFKQVLPCFDP 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	94/307 (31%)
		TM helix 1	76..102	CDD:320224	9/25 (36%)
		TM helix 2	109..135	CDD:320224	15/25 (60%)
		TM helix 3	147..177	CDD:320224	10/33 (30%)
		TM helix 4	189..209	CDD:320224	2/19 (11%)
		TM helix 5	239..268	CDD:320224	5/32 (16%)
		TM helix 6	284..314	CDD:320224	11/29 (38%)
		TM helix 7	326..351	CDD:320224	10/24 (42%)
sNPF-R	XP_320180.2	None