Protein Alignment AstA-R1 and Ackr3

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_031748.2
• Gene: Ackr3 / 12778
• MGIID: 109562
• Length: 362
• Species: Mus musculus
• Alignment Length: 352
• Identity: 85/352 - (24%)
• Similarity: 163/352 - (46%)
• Gaps: 62/352 - (17%)

  Fly    41 NYAFTSEHTD-HSDHNANDSMEYDA--------ESVALERIVSTIVPVFFGIIGFAGLLGNGLVI 96
            :||....::| :...|::|.:..|.        ::|.|..:  :.:.:|..:|   |::.|.:|:
Mouse     7 DYAEPGNYSDINWPCNSSDCIVVDTVQCPTMPNKNVLLYTL--SFIYIFIFVI---GMIANSVVV 66

  Fly    97 LVVVANQQMRST---TNLLIINLAVSDILFVIFCVPFTATDYVL-PEWPFGNVWCKFVQYMIVVT 157
            .|   |.|.::|   |:..|:|||::| |:|:..:|......|. .:||.|.:.||....:..:.
Mouse    67 WV---NIQAKTTGYDTHCYILNLAIAD-LWVVITIPVWVVSLVQHNQWPMGELTCKITHLIFSIN 127

  Fly   158 CHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQYHG 222
            ...|::.|..||.||:|::.:...:.|.:.:....:..:..|:.....::|.  ::.::......
Mouse   128 LFGSIFFLACMSVDRYLSITYFTGTSSYKKKMVRRVVCILVWLLAFFVSLPD--TYYLKTVTSAS 190

  Fly   223 NAGTAC-VFSTEEEI--WSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRK 284
            |..|.| .|..|..|  | |:|.::...:..:..|.|:|...|. :|||. .||.|.:....|||
Mouse   191 NNETYCRSFYPEHSIKEW-LIGMELVSVILGFAVPFTIIAIFYF-LLARA-MSASGDQEKHSSRK 252

  Fly   285 GKRRVTRMVVVVVLAFAICWLPIHVILVLKALN--------------LYGGSHLSVIIQIISHVV 335
                   ::...|:.|.:||||.|.:::|...:              |:...|::..:.::
Mouse   253 -------IIFSYVVVFLVCWLPYHFVVLLDIFSILHYIPFTCQLENVLFTALHVTQCLSLV---- 306

  Fly   336 AYTNSCINPILYAFLSDNFR----KAF 358
               :.|:||:||:|::.|:|    |||
Mouse   307 ---HCCVNPVLYSFINRNYRYELMKAF 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	75/307 (24%)
		TM helix 1	76..102	CDD:320224	6/25 (24%)
		TM helix 2	109..135	CDD:320224	9/25 (36%)
		TM helix 3	147..177	CDD:320224	9/29 (31%)
		TM helix 4	189..209	CDD:320224	1/19 (5%)
		TM helix 5	239..268	CDD:320224	7/28 (25%)
		TM helix 6	284..314	CDD:320224	8/29 (28%)
		TM helix 7	326..351	CDD:320224	6/24 (25%)
Ackr3	NP_031748.2	7tmA_ACKR3_CXCR7	45..326	CDD:320118	74/308 (24%)
		TM helix 1	46..72	CDD:320118	7/33 (21%)
		TM helix 2	79..103	CDD:320118	9/24 (38%)
		TM helix 3	117..147	CDD:320118	9/29 (31%)
		TM helix 4	160..181	CDD:320118	2/22 (9%)
		TM helix 5	209..236	CDD:320118	6/27 (22%)
		TM helix 6	245..275	CDD:320118	10/36 (28%)
		TM helix 7	294..319	CDD:320118	7/31 (23%)
		C-terminal cytoplasmic tail. /evidence=ECO:0000250	324..362		3/7 (43%)