Protein Alignment AstA-R1 and AstA-R1

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: XP_061501722.1
• Gene: AstA-R1 / 1274331
• VectorBaseID: AGAMI1_005849
• Length: 381
• Species: Anopheles gambiae
• Alignment Length: 395
• Identity: 255/395 - (64%)
• Similarity: 286/395 - (72%)
• Gaps: 33/395 - (8%)

  Fly     4 HQSLALLLATLISSWPKASWGATGNGSIISVSNSSGNNYAFTSEHTDHSDHNANDSMEYDAESVA 68
            |..|.:|:..          |..||.|...:.     ||.|.:|..            |...:..
Mosquito    16 HHQLPMLMPD----------GTLGNSSWTDLL-----NYTFENEAL------------YHVNTST 53

  Fly    69 LERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTAT 133
            :|||||.:||||||.||.|||||||||:|||.|||.|||||||||||||.:|:|||:|||||||.
Mosquito    54 IERIVSLMVPVFFGFIGLAGLLGNGLVVLVVAANQSMRSTTNLLIINLAAADLLFVVFCVPFTAV 118

  Fly   134 DYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCA 198
            ||||||||||..||||||||||||.|.|.|||||||.|||||||||:||||:||||||:|||...
Mosquito   119 DYVLPEWPFGEYWCKFVQYMIVVTAHASAYTLVLMSLDRFLAVVHPITSMSIRTERNASLAICLT 183

  Fly   199 WITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYM 263
            |..|:|||||||:||.|..|...|...|||:| ...|.:|||.|.|||||||||.||:||.||||
Mosquito   184 WFVILTTAIPVAISHGVLFYPRQGGYYTACLF-LHNEGYSLVAFHVSFFLSSYVVPLSLISFLYM 247

  Fly   264 GMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVII 328
            ||||||||.|||.:.|||||:||:|||||||||||.||.||.||.|||:||:|.|||.:|.|:|.
Mosquito   248 GMLARLWKGAPGGRASAESRRGKKRVTRMVVVVVLVFAFCWCPIQVILLLKSLKLYGLTHASIIF 312

  Fly   329 QIISHVVAYTNSCINPILYAFLSDNFRKAFR---KVVWCGS-PPPLMTNQQVTKTTRTATGNGTS 389
            ||:|||:|||||||||:||||||||||||||   ||||||. |||.:.....|||||| ||||||
Mosquito   313 QIVSHVLAYTNSCINPVLYAFLSDNFRKAFRKVSKVVWCGKPPPPTIPPAAQTKTTRT-TGNGTS 376

  Fly   390 NIEML 394
            |.:.|
Mosquito   377 NADAL 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	212/282 (75%)
		TM helix 1	76..102	CDD:320224	20/25 (80%)
		TM helix 2	109..135	CDD:320224	20/25 (80%)
		TM helix 3	147..177	CDD:320224	25/29 (86%)
		TM helix 4	189..209	CDD:320224	12/19 (63%)
		TM helix 5	239..268	CDD:320224	23/28 (82%)
		TM helix 6	284..314	CDD:320224	22/29 (76%)
		TM helix 7	326..351	CDD:320224	19/24 (79%)
AstA-R1	XP_061501722.1	None