Protein Alignment AstA-R1 and LOC1270512

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: XP_061518622.1
• Gene: LOC1270512 / 1270512
• VectorBaseID: AGAMI1_007575
• Length: 805
• Species: Anopheles gambiae
• Alignment Length: 662
• Identity: 128/662 - (19%)
• Similarity: 198/662 - (29%)
• Gaps: 328/662 - (49%)

  Fly     6 SLAL--LLATLISSWPKASWGATGNGSIISVSNSSGNNYAFTSEHTDHS---DHNANDSMEYDAE 65
            ||||  ||...||:....:...:|||     .:::||....|...|..|   |....:.:
Mosquito    93 SLALGELLRDNISATVVGTHNLSGNG-----RSAAGNLPPATGTGTAGSRGGDGTFQNQL----- 147

  Fly    66 SVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPF 130
                      |:|: :.||....::||.||||.:..|::||:.||:.::|||:||:|..:||:||
Mosquito   148 ----------IIPL-YAIIFLLSVVGNLLVILTLAQNKRMRTVTNVYLLNLAISDLLLGVFCMPF 201

  Fly   131 TATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAI 195
            |....||..:.||:|.||.:.|...|:...:|:|||.:|.:|:.|:..|::|...:|:.:|...|
Mosquito   202 TLAGQVLRRFVFGSVMCKLIPYFQAVSVSVAVWTLVAISLERYFAICRPLSSRRWQTQFHAYKMI 266

  Fly   196 MCAW---------ITIVTTAIPV------------------------------------------ 209
            ...|         :..|...:||
Mosquito   267 GLVWTVSFLANSPLGYVQRLLPVGRSTGQMKCREEWPSPAWERAYVLFHDVGLLFLPLLTMGFAY 331

  Fly   210 ---------ALSHSVR---IYQ----YHGNAG--------------------------------- 225
                     .|.|.::   :||    .||..|
Mosquito   332 SMIVSKLWRGLRHEIKHSSLYQQTSRQHGTGGQGSSVGGAPTGAAAGSVGTVSGEQHCSGDTGKP 396

  Fly   226 ---------------------------TACV-------------FS------------------- 231
                                       ||.|             ||
Mosquito   397 PKPPGGKRHEPGFVLTSSLKKAPFKSSTAVVNFASNNNTINKSNFSGAGSGSSSNGAGSSGSSNG 461

  Fly   232 ----------------------TEEEIWSLVGFQVSFFL------------------SSYVAPLT 256
                                  .|.....|.||: .||.                  |:..||..
Mosquito   462 SNGGGCNGSGADQRTHYCGGAGCETRPGRLRGFR-HFFAKQHHQHVGLCRNQRYQRSSTAAAPEG 525

  Fly   257 L---------------------ICFLY-------------------------------------- 262
            |                     .|..:
Mosquito   526 LPELAETKFDESASVGQQHPYHHCHCHHAHGYHHHHHRLPTSTIVKSTQQDAKHEIVLGTGEPGP 590

  Fly   263 ----MGMLARLWKSAPG------------CKPSA--------------------ESRKGKRRVTR 291
                .|....|..:.||            |.|||                    :|.:.|::|.|
Mosquito   591 GLEPAGDAVLLPGAPPGSAATAPETGQGDCDPSALNPDPAYQFSRHAIRSTYMDKSIEAKKKVIR 655

  Fly   292 MVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQ----IISHVVAYTNSCINPILYAFLSD 352
            |:.|:::.|.:||.|:|   :|..:.||..:.:...:.    .:..::||.:||.|||.|.|::.
Mosquito   656 MLFVIIVEFFVCWAPLH---ILNTVYLYSPTFVYQYVNSSGIALVQLMAYISSCCNPITYCFMNR 717

  Fly   353 NFRKAFRKVVWC 364
            .||:||..|..|
Mosquito   718 RFRQAFLGVFSC 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	107/580 (18%)
		TM helix 1	76..102	CDD:320224	10/25 (40%)
		TM helix 2	109..135	CDD:320224	13/25 (52%)
		TM helix 3	147..177	CDD:320224	11/29 (38%)
		TM helix 4	189..209	CDD:320224	4/28 (14%)
		TM helix 5	239..268	CDD:320224	11/109 (10%)
		TM helix 6	284..314	CDD:320224	10/29 (34%)
		TM helix 7	326..351	CDD:320224	9/28 (32%)
LOC1270512	XP_061518622.1	None