Protein Alignment AstA-R1 and Cckar

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_033957.1
• Gene: Cckar / 12425
• MGIID: 99478
• Length: 436
• Species: Mus musculus
• Alignment Length: 366
• Identity: 93/366 - (25%)
• Similarity: 161/366 - (43%)
• Gaps: 75/366 - (20%)

  Fly    74 STIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLP 138
            |.:..:.:..|....:|||.|||.|::.|::||:.||:.:::|||||::..:||:||.....:|.
Mouse    41 SAVQILLYSFIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK 105

  Fly   139 EWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIV 203
            ::.||:..||...|.:..:...|.:.||.:|.:|:.|:..|:.|...:|:.:|...|...|....
Mouse   106 DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSF 170

  Fly   204 TTAIPVAL-SHSVRIYQYHGNAGTACVF----STEEEIWSLVGFQVSFFLSSYVAPLT--LICF- 260
            |...|..: |:.|...:.:......|.|    ...::.|......:.|.:...|..:.  ||..
Mouse   171 TIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLIPGVVMVVAYGLISLE 235

  Fly   261 LYMGML-----------ARL--------------WKSAPGC-----KP----------------- 278
            ||.|:.           .||              ::.:.||     :|
Mouse   236 LYQGIKFDASQKKSAKEKRLSSGGGGGGGSSSSRYEDSDGCYLQKSRPPRKLELQQLSTSSSGGR 300

  Fly   279 --------SAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNL------YGGSHLSVIIQ 329
                    ||.:...|:||.||::|:|:.|.:||:||......:|.:.      ..|:.:|.|:
Mouse   301 INRIRSSGSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFIL- 364

  Fly   330 IISHVVAYTNSCINPILYAFLSDNFRKAFRKVV-WCGSPPP 369
                :::||:||:|||:|.|::..||..|.... .|.:|.|
Mouse   365 ----LLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGP 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	88/351 (25%)
		TM helix 1	76..102	CDD:320224	8/25 (32%)
		TM helix 2	109..135	CDD:320224	11/25 (44%)
		TM helix 3	147..177	CDD:320224	9/29 (31%)
		TM helix 4	189..209	CDD:320224	4/19 (21%)
		TM helix 5	239..268	CDD:320224	7/42 (17%)
		TM helix 6	284..314	CDD:320224	12/29 (41%)
		TM helix 7	326..351	CDD:320224	10/24 (42%)
Cckar	NP_033957.1	CholecysA-Rec_N	1..47	CDD:462713	1/5 (20%)
		7tm_GPCRs	42..389	CDD:475119	88/351 (25%)
		TM helix 1	44..68	CDD:410628	8/23 (35%)
		TM helix 2	77..99	CDD:410628	10/21 (48%)
		TM helix 3	115..137	CDD:410628	5/21 (24%)
		TM helix 4	160..176	CDD:410628	3/15 (20%)
		TM helix 5	207..230	CDD:410628	3/22 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..280		4/27 (15%)
		TM helix 6	320..342	CDD:410628	9/21 (43%)
		TM helix 7	357..382	CDD:410628	12/29 (41%)