Protein Alignment AstA-R1 and CCR6

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_004358.2
• Gene: CCR6 / 1235
• HGNCID: 1607
• Length: 374
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 100/392 - (25%)
• Similarity: 186/392 - (47%)
• Gaps: 55/392 - (14%)

  Fly    38 SGNNYAFTSEHTDHSDHNANDSMEY---DAESV-----ALERIVSTIVPVFFGIIGFAGLLGNGL 94
            ||.:..|:.......|:..:.:..|   |:|.:     .:.:.....||:.:.:|...|||||.|
Human     2 SGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNIL 66

  Fly    95 VILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCH 159
            |::.....::.||.|::.::|:|::|||||: .:||.|..:....|.|.|..||.::.:..:..:
Human    67 VVITFAFYKKARSMTDVYLLNMAIADILFVL-TLPFWAVSHATGAWVFSNATCKLLKGIYAINFN 130

  Fly   160 CSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIY--QYHG 222
            |.:..|..:|.||::|:|....|..||:.......|:|    :|...:.|.:|.|..::  :|:.
Human   131 CGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIIC----LVVWGLSVIISSSTFVFNQKYNT 191

  Fly   223 NAGTAC--VFSTEEE--IWSL--VGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAE 281
            .....|  .:.|..|  .|.|  :|.::.|   .:..||..:.|.|..::          |...:
Human   192 QGSDVCEPKYQTVSEPIRWKLLMLGLELLF---GFFIPLMFMIFCYTFIV----------KTLVQ 243

  Fly   282 SRKGKR-RVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSV-------IIQIISHVVAYT 338
            ::..|| :..|:::.|||.|..|.:|.:::|::.|.|| |..:.|.       ..:.::.|:|:.
Human   244 AQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANL-GKMNRSCQSEKLIGYTKTVTEVLAFL 307

  Fly   339 NSCINPILYAFLSDNFRKAFRKV---VWC--------GSPPPLMTNQQVTK-TTRTATGNGTSNI 391
            :.|:||:||||:...||..|.|:   :||        |.......::.::: |:.||..:..|:.
Human   308 HCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSF 372

  Fly   392 EM 393
            .|
Human   373 TM 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	83/298 (28%)
		TM helix 1	76..102	CDD:320224	10/25 (40%)
		TM helix 2	109..135	CDD:320224	11/25 (44%)
		TM helix 3	147..177	CDD:320224	8/29 (28%)
		TM helix 4	189..209	CDD:320224	3/19 (16%)
		TM helix 5	239..268	CDD:320224	7/30 (23%)
		TM helix 6	284..314	CDD:320224	10/30 (33%)
		TM helix 7	326..351	CDD:320224	9/31 (29%)
CCR6	NP_004358.2	7tmA_CCR6	47..327	CDD:341330	83/298 (28%)
		TM helix 1	47..74	CDD:341330	10/26 (38%)
		TM helix 2	81..106	CDD:341330	11/25 (44%)
		TM helix 3	118..148	CDD:341330	8/29 (28%)
		TM helix 4	162..184	CDD:341330	6/25 (24%)
		TM helix 5	211..240	CDD:341330	7/41 (17%)
		TM helix 6	247..277	CDD:341330	10/29 (34%)
		TM helix 7	295..320	CDD:341330	9/24 (38%)