Protein Alignment AstA-R1 and CCR3

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: XP_016861174.1
• Gene: CCR3 / 1232
• HGNCID: 1604
• Length: 410
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 88/355 - (24%)
• Similarity: 180/355 - (50%)
• Gaps: 39/355 - (10%)

  Fly    62 YDAESVALER-----IVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDI 121
            ||...:..|:     :::..||..:.::...|||||.:|:::::..:::|..||:.::|||:||:
Human    72 YDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDL 136

  Fly   122 LFVIFCVPFTATDYVL-PEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSL 185
            ||:: .:||. ..||. ..|.||:..||.:........:..::.::|::.||:||:||.|.::..
Human   137 LFLV-TLPFW-IHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRA 199

  Fly   186 RTERNATLAIMCAWITIVTTAIPVALSHSV-RIYQYHGNAGTAC-VFSTEEEIWSLVGFQ-VSFF 247
            ||.....:..:..|...|..|:|..:.:.. .:::     .|.| ....|:.::|...|. :...
Human   200 RTVTFGVITSIVTWGLAVLAALPEFIFYETEELFE-----ETLCSALYPEDTVYSWRHFHTLRMT 259

  Fly   248 LSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILV 312
            :...|.||.::...|.|::..|.:    | ||    |.|.:..|::.|::..|.|.|.|.:|.::
Human   260 IFCLVLPLLVMAICYTGIIKTLLR----C-PS----KKKYKAIRLIFVIMAVFFIFWTPYNVAIL 315

  Fly   313 LKALN--LYG-----GSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRK------VVWC 364
            |.:..  |:|     ..||. ::.:::.|:||::.|:||::|||:.:.|||..|.      ::..
Human   316 LSSYQSILFGNDCERSKHLD-LVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHL 379

  Fly   365 GSPPPLMTNQQVTKTTRTATGNGTSNIEML 394
            |...|.:.::::.:|:..:.......:.::
Human   380 GRYIPFLPSEKLERTSSVSPSTAEPELSIV 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	81/293 (28%)
		TM helix 1	76..102	CDD:320224	8/25 (32%)
		TM helix 2	109..135	CDD:320224	11/25 (44%)
		TM helix 3	147..177	CDD:320224	7/29 (24%)
		TM helix 4	189..209	CDD:320224	3/19 (16%)
		TM helix 5	239..268	CDD:320224	6/29 (21%)
		TM helix 6	284..314	CDD:320224	9/29 (31%)
		TM helix 7	326..351	CDD:320224	9/24 (38%)
CCR3	XP_016861174.1	7tmA_CCR3	90..367	CDD:341339	81/293 (28%)
		TM helix 1	90..117	CDD:341339	8/26 (31%)
		TM helix 2	124..149	CDD:341339	11/26 (42%)
		TM helix 3	161..191	CDD:341339	7/29 (24%)
		TM helix 4	203..225	CDD:341339	4/21 (19%)
		TM helix 5	251..280	CDD:341339	6/28 (21%)
		TM helix 6	287..317	CDD:341339	9/29 (31%)
		TM helix 7	335..360	CDD:341339	9/25 (36%)