Protein Alignment AstA-R1 and Agtr1b

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_780295.2
• Gene: Agtr1b / 11608
• MGIID: 87965
• Length: 359
• Species: Mus musculus
• Alignment Length: 314
• Identity: 83/314 - (26%)
• Similarity: 153/314 - (48%)
• Gaps: 27/314 - (8%)

  Fly    63 DAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFC 127
            |.........:..::|..:.||...|:.||.||::|:....::::..::.::|||::|:.|:: .
Mouse    17 DCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLL-T 80

  Fly   128 VP----FTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTE 188
            :|    :||.:|   :|||||..||.....:....:.||:.|..:|.||:||:|||:.|...||.
Mouse    81 LPLWAVYTAMEY---QWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTM 142

  Fly   189 RNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEEEIWSL-VGFQVSFFLSSYV 252
            ..|.:..:..|:.....::|..:..:|  |.......|.|.|..|.:..:| :|..::..:..:|
Mouse   143 LVAKVTCIIIWLMAGLASLPAVIHRNV--YFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFV 205

  Fly   253 APLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRR---VTRMVVVVVLAFAICWLPIHVILVLK 314
            .|..:|...|    ..:||:   .|.:.:.:|...|   :.|:::.:||.|...|:|..:...|.
Mouse   206 FPFVIILTSY----TLIWKA---LKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFSFLD 263

  Fly   315 ALNLYGGSHLSVIIQI------ISHVVAYTNSCINPILYAFLSDNFRKAFRKVV 362
            .|...|..|...|..:      |:..:||.|:|:||:.|.||...|::.|.:::
Mouse   264 VLIQLGVIHDCEIADVVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLL 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	81/296 (27%)
		TM helix 1	76..102	CDD:320224	9/25 (36%)
		TM helix 2	109..135	CDD:320224	8/29 (28%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	2/19 (11%)
		TM helix 5	239..268	CDD:320224	6/29 (21%)
		TM helix 6	284..314	CDD:320224	8/32 (25%)
		TM helix 7	326..351	CDD:320224	10/30 (33%)
Agtr1b	NP_780295.2	7tmA_AT1R	29..313	CDD:320320	81/296 (27%)
		TM helix 1	30..56	CDD:320320	9/25 (36%)
		TM helix 2	63..88	CDD:320320	6/25 (24%)
		TM helix 3	101..131	CDD:320320	10/29 (34%)
		TM helix 4	144..165	CDD:320320	3/20 (15%)
		TM helix 5	192..221	CDD:320320	6/32 (19%)
		TM helix 6	233..263	CDD:320320	7/29 (24%)
		TM helix 7	281..306	CDD:320320	9/24 (38%)