DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and LOC110438944

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	XP_021328259.1	Gene:	LOC110438944 / 110438944	-ID:	-	Length:	383	Species:	Danio rerio

Alignment Length:	299	Identity:	110/299 - (36%)
Similarity:	178/299 - (59%)	Gaps:	15/299 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 RIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRS-TTNLLIINLAVSDILFVIFCVPFTATD 134
            ::.|.|:.:.|.:|...|.:||.||:.|::.|.||.: :|||.|:||.::|:.|::||||..||.
Zfish    35 KVESVIISLIFSMIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATI 99

  Fly   135 YVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAW 199
            |.:.||.||...||.|.::|.:|.:.|::||..:|.||:||:.:|:.|...||.|||..:|...|
Zfish   100 YTMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSRETRTPRNALTSISLVW 164

  Fly   200 ITIVTTAIPVALSHSVRIYQYHGNAG-TACVFSTEEEIWSL---VGFQVSFFLSSYVAPLTLICF 260
            ...:..:.|. ||:    ||.....| |.|:     ..||:   ....:..|:..|:.|:.::..
Zfish   165 ALSLFFSSPY-LSY----YQQMDLDGTTVCI-----PAWSVHHRQAMDICTFIFGYLIPVLILGI 219

  Fly   261 LYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLS 325
            .|...:..||.|....:..:||||.||:||:|:::|.:.|.:||||.|::::......:..:|.:
Zfish   220 TYARTIRYLWTSVDPMQDMSESRKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWFGHFPLNHTT 284

  Fly   326 VIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWC 364
            .:::|:||:|||.|||:|||:||.:|.:|||.|:||..|
Zfish   285 YVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGC 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	61/161 (38%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	95/260 (37%)
LOC110438944	XP_021328259.1	7tmA_Gal2_Gal3_R	39..317	CDD:320225	105/287 (37%)
		TM helix 1	40..66	CDD:320225	9/25 (36%)
		TM helix 2	74..100	CDD:320225	14/25 (56%)
		TM helix 3	112..142	CDD:320225	13/29 (45%)
		TM helix 4	154..174	CDD:320225	5/19 (26%)
		TM helix 5	198..227	CDD:320225	4/28 (14%)
		TM helix 6	243..273	CDD:320225	13/29 (45%)
		TM helix 7	285..310	CDD:320225	14/24 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580808
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9CW
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1294084at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840