Protein Alignment AstA-R1 and CCR9

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: NP_112477.1
• Gene: CCR9 / 10803
• HGNCID: 1610
• Length: 369
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 77/336 - (22%)
• Similarity: 159/336 - (47%)
• Gaps: 43/336 - (12%)

  Fly    45 TSEHTDHSDHNANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTT 109
            ||...|:.:.|..|   :..|...:.:..|..:|..:.::...|.|||.|||||.....::::.|
Human    22 TSSMEDYVNFNFTD---FYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMT 83

  Fly   110 NLLIINLAVSDILFVIFCVPF---TATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFD 171
            ::.::|||::|:||:: .:||   .|.|    :|.|....||.|..|..:..:..|..::.:|.|
Human    84 DMFLLNLAIADLLFLV-TLPFWAIAAAD----QWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVD 143

  Fly   172 RFLAVVHPVTSMSLRTERNATLAIMC--AWITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEE 234
            |::|:...:.:.:.|.:|.....::|  .|:......||..|...::  :..|.|....|:.::|
Human   144 RYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIK--EESGIAICTMVYPSDE 206

  Fly   235 --EIWSLV---GFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVV 294
              ::.|.|   ...:.|||     |..::...|..::..|.::         .:..|.:..::.:
Human   207 STKLKSAVLTLKVILGFFL-----PFVVMACCYTIIIHTLIQA---------KKSSKHKALKVTI 257

  Fly   295 VVVLAFAICWLPIHVILVLKALNLYG--------GSHLSVIIQIISHVVAYTNSCINPILYAFLS 351
            .|:..|.:...|.:.||:::.::.|.        .:::.:..| ::..:|:.:||:||:||.|:.
Human   258 TVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQ-VTQTIAFFHSCLNPVLYVFVG 321

  Fly   352 DNFRKAFRKVV 362
            :.||:...|.:
Human   322 ERFRRDLVKTL 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	69/300 (23%)
		TM helix 1	76..102	CDD:320224	10/25 (40%)
		TM helix 2	109..135	CDD:320224	10/28 (36%)
		TM helix 3	147..177	CDD:320224	9/29 (31%)
		TM helix 4	189..209	CDD:320224	4/21 (19%)
		TM helix 5	239..268	CDD:320224	6/31 (19%)
		TM helix 6	284..314	CDD:320224	6/29 (21%)
		TM helix 7	326..351	CDD:320224	9/24 (38%)
CCR9	NP_112477.1	7tmA_CCR9	49..328	CDD:320302	69/300 (23%)
		TM helix 1	49..76	CDD:320302	10/26 (38%)
		TM helix 2	83..108	CDD:320302	9/25 (36%)
		TM helix 3	119..149	CDD:320302	9/29 (31%)
		TM helix 4	163..185	CDD:320302	4/21 (19%)
		TM helix 5	211..240	CDD:320302	7/33 (21%)
		TM helix 6	247..277	CDD:320302	6/29 (21%)
		TM helix 7	296..321	CDD:320302	9/25 (36%)