DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and LOC100535160

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	XP_003201711.2	Gene:	LOC100535160 / 100535160	-ID:	-	Length:	351	Species:	Danio rerio

Alignment Length:	337	Identity:	88/337 - (26%)
Similarity:	158/337 - (46%)	Gaps:	63/337 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 IVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEW 140
            |:|.|.|.:...||:|| :::||.:.....::..::.:.||||:|::.|| .:||     ::.:|
Zfish    48 ILPAFIGFLCSTGLVGN-VLVLVTILRSAKKTVPDVYVGNLAVADLVHVI-VMPF-----LIHQW 105

  Fly   141 PFGNVWCKFVQYMIVVT----CH---CSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAI-MC 197
            ..|..|........::|    |:   |:. .:..||.||:||:|||...:|||| |:.|:.| :.
Zfish   106 ARGGHWVFGSSLCTIITSLDNCNQVACAA-VMTAMSLDRYLALVHPFRLLSLRT-RSRTIRINLF 168

  Fly   198 AWITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEEEIW-SLVGFQVSFFLSSYVAPLTLICFL 261
            .|.......:|..:...|..::....:.:..:.|.::.:| :|.....||||     ||.||...
Zfish   169 VWAASFIMVLPAWVHAKVIRFRDGLESCSLNLVSPKQVLWYTLYQTVTSFFL-----PLPLILTC 228

  Fly   262 YMGMLARLWKSAPGCKPSAESRKGKR--------------RVTRMVVVVVLAFAICWLPIHVILV 312
            |:.:|...|:.         .||.|:              |:|:||:|:|..|.:...|.|::.:
Zfish   229 YILILCYTWRM---------YRKNKKAHRYNTSLPRERVVRLTKMVLVLVAVFLVSVGPYHILQL 284

  Fly   313 LK------ALNLYGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPPPLM 371
            :.      :|..:...:|||.:       :|..|.|||.:|..||.:||   .::| |...|.:.
Zfish   285 VNLSVPRPSLAYHTCYYLSVCL-------SYAASSINPFIYILLSGHFR---HRLV-CRDTPSMP 338

  Fly   372 TNQQVTKTTRTA 383
            :.::..:..|::
Zfish   339 SVEREIQAPRSS 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	42/165 (25%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	73/284 (26%)
LOC100535160	XP_003201711.2	7tmA_MCHR2	47..329	CDD:320461	84/313 (27%)
		TM helix 1	48..74	CDD:320461	10/26 (38%)
		TM helix 2	80..106	CDD:320461	9/31 (29%)
		TM helix 3	118..148	CDD:320461	9/30 (30%)
		TM helix 4	160..180	CDD:320461	3/19 (16%)
		TM helix 5	206..235	CDD:320461	12/33 (36%)
		TM helix 6	256..286	CDD:320461	9/29 (31%)
		TM helix 7	297..322	CDD:320461	9/31 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100