DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and oprk1

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_001305708.1	Gene:	oprk1 / 100489465	XenbaseID:	XB-GENE-1011503	Length:	420	Species:	Xenopus tropicalis

Alignment Length:	342	Identity:	110/342 - (32%)
Similarity:	181/342 - (52%)	Gaps:	7/342 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KASWGATGNGSIISVSNSS-GNNYAFTSEHTDHSDHNANDSMEY-DAESVALERIVSTIVPVFFG 82
            :|..|:|.:.|......|| ..|.::.....||.:.:|...:.. :....::...:|.|:...:.
Frog    20 RAPVGSTCSSSCAPACPSSCFPNTSWLLGWDDHDNVSAYPDLPLNEGNHTSISPTISVIITAVYS 84

  Fly    83 IIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLPEWPFGNVWC 147
            ::...||:||.||:.|::...:|::.||:.|.|||::|.| |...:||.:|.:::..||||:|.|
Frog    85 MVFVVGLVGNALVMFVIIRYTKMKTATNIYIFNLALADAL-VTTTMPFQSTSFLMNSWPFGDVLC 148

  Fly   148 KFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIVTTAIPVALS 212
            |.|..:.......|::||.:||.||::||.|||.::..||...|....:|.|:...:..|...:.
Frog   149 KIVVSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKCINICIWMLSSSVGISAIVL 213

  Fly   213 HSVRIYQYHGNAGTACVFSTEEEIWSLVGFQVSFFLSSYVAPLTLICFLYMGMLARLWKSAPGCK 277
            ...:|..  |:...|..|.|....|..| .::..|:.:::.|:.:|...|..|:.|| ||.....
Frog   214 GGTKISD--GSTECALQFPTHYWYWDTV-MKMCVFIFAFIIPVFIITICYTLMILRL-KSVRLLS 274

  Fly   278 PSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSVIIQIISHVVAYTNSCI 342
            .|.|..:..||:||:|:|||..|.:||.|||:.::::||.....|...|.|......:.||||.:
Frog   275 GSREKDRNLRRITRLVLVVVAVFIVCWTPIHIFVLVEALVDVPQSIAVVSIYYFCIALGYTNSSL 339

  Fly   343 NPILYAFLSDNFRKAFR 359
            ||||||||.:||::.|:
Frog   340 NPILYAFLDENFKRCFK 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	52/156 (33%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	88/255 (35%)
oprk1	NP_001305708.1	7tm_4	88..>289	CDD:304433	67/205 (33%)
oprk1	NP_001305708.1	7tm_1	93..344	CDD:278431	88/255 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010