DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstA-R1 and sstr3

DIOPT Version :9

Sequence 1:	NP_524700.1	Gene:	AstA-R1 / 44126	FlyBaseID:	FBgn0266429	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	XP_004913945.1	Gene:	sstr3 / 100488886	XenbaseID:	XB-GENE-984793	Length:	403	Species:	Xenopus tropicalis

Alignment Length:	323	Identity:	103/323 - (31%)
Similarity:	162/323 - (50%)	Gaps:	40/323 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 NANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVV---VANQQMRSTTNLLIINL 116
            |.|.|...:..|..|      ::|:.:.::...||.||.|||.:.   .|.|  .|.|.|.|:||
Frog    22 NTNISFNQNGTSPGL------LIPLVYLVVCAVGLWGNTLVIYLAWRSPAGQ--NSVTALYILNL 78

  Fly   117 AVSDILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVT 181
            |::|.||:: .:||.|....|..||||:..|:.|..:..|....|::.|.::||||:||||.|:.
Frog    79 ALADDLFML-GLPFLAAQNALSYWPFGSPACRLVMTLDAVNQFTSIFCLTVLSFDRYLAVVRPIQ 142

  Fly   182 SMSLRTERNATLAIMCAWITIVTTAIPVALSHSVRIYQYHGNAGTACVFSTEE--EIWSLVGFQV 244
            |...|..:.|....:..||......:||.....|     .|:.|| |..:..|  ::|. .||.:
Frog   143 SAKWRKPKVAKCVNVTVWILSFLVVLPVVFFSGV-----PGDTGT-CHIAWPEPAQMWR-TGFIL 200

  Fly   245 SFFLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKG-KRRVTRMVVVVVLAFAICWLPIH 308
            ......:..||.:||..::.::|::..|....:.:...|:| :|:||:||.:.|.||.:||.|.:
Frog   201 YTAALGFFCPLLVICICHLLIVAQVRSSGKRVRVAPNRRQGPERKVTKMVALTVTAFVLCWFPFY 265

  Fly   309 VILVLKAL-------NLYGGSHLSVIIQIISHVVA--YTNSCINPILYAFLSDNFRKAFRKVV 362
            .:.::..|       .|||         :.|.|||  |.|||:|||:||.|:..|::..|:|:
Frog   266 ALNIINLLWPLPESPKLYG---------LYSFVVALSYANSCLNPIIYALLARPFQRGLRRVL 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	55/161 (34%)
AstA-R1	NP_524700.1	7tm_1	91..347	CDD:278431	89/270 (33%)
sstr3	XP_004913945.1	7tmA_SSTR3	36..315	CDD:320638	97/303 (32%)
		TM helix 1	37..63	CDD:320638	8/25 (32%)
		TM helix 2	71..97	CDD:320638	12/26 (46%)
		TM helix 3	108..138	CDD:320638	11/29 (38%)
		TM helix 4	150..172	CDD:320638	5/21 (24%)
		TM helix 5	195..224	CDD:320638	6/29 (21%)
		TM helix 6	241..271	CDD:320638	12/29 (41%)
		TM helix 7	283..308	CDD:320638	15/33 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100