Protein Alignment AstA-R1 and oprm1

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: XP_002933909.1
• Gene: oprm1 / 100487937
• XenbaseID: XB-GENE-1011391
• Length: 388
• Species: Xenopus tropicalis
• Alignment Length: 342
• Identity: 117/342 - (34%)
• Similarity: 185/342 - (54%)
• Gaps: 26/342 - (7%)

  Fly    55 NANDSMEYDAESVALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVS 119
            |.:::...|::|:    |::.|:...:.:|...||.||.||:.|:|...:|::.||:.|.|||::
 Frog    54 NQSETFPEDSDSI----IIAIIITALYSMICVMGLFGNVLVMYVIVRYTKMKTATNIYIFNLALA 114

  Fly   120 DILFVIFCVPFTATDYVLPEWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMS 184
            |.| ....:||.:.:|::..|||||:.||.|..:.......|::||..||.||::||.|||.::.
 Frog   115 DAL-ATSTLPFQSVNYLMGTWPFGNIVCKIVISIDYYNMFTSIFTLTTMSVDRYIAVCHPVKALD 178

  Fly   185 LRTERNATLAIMCAWITIVTTAIPV---ALSHSVRIYQYHGNAGTACVFSTEEEIWSLVGFQVSF 246
            .||.|||.:..:|.||......:||   |.:.|.|     |:...|.:|......|..: .::..
 Frog   179 FRTPRNAKIVNVCNWILSSAIGLPVMFMATTKSER-----GSTDCALLFPHPSWYWDNL-LKICV 237

  Fly   247 FLSSYVAPLTLICFLYMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVIL 311
            |:.:::.|:.:|...|..|:.|| ||......|.|..:..||:||||:|||..|.:||.|||:.:
 Frog   238 FIFAFIMPVLIITVCYGMMILRL-KSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV 301

  Fly   312 VLKALNLYGGSHLSVIIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKVVWCGSPPPLMTNQQV 376
            ::|||.....|....:...:...:.|||||:||:|||||.:||::.||:  :|  .|...|.:|.
 Frog   302 IIKALINIPPSLFQTVTWHVCIALGYTNSCLNPVLYAFLDENFKRCFRE--FC--IPTSSTIEQQ 362

  Fly   377 TKT-------TRTATGN 386
            ..|       .|.:|.|
 Frog   363 NSTRMRHNTRDRASTAN 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	103/285 (36%)
		TM helix 1	76..102	CDD:320224	10/25 (40%)
		TM helix 2	109..135	CDD:320224	10/25 (40%)
		TM helix 3	147..177	CDD:320224	11/29 (38%)
		TM helix 4	189..209	CDD:320224	6/19 (32%)
		TM helix 5	239..268	CDD:320224	5/28 (18%)
		TM helix 6	284..314	CDD:320224	15/29 (52%)
		TM helix 7	326..351	CDD:320224	11/24 (46%)
oprm1	XP_002933909.1	7tmA_Mu_opioid_R	73..348	CDD:320218	102/282 (36%)
		TM helix 1	73..97	CDD:320218	9/23 (39%)
		TM helix 2	104..130	CDD:320218	10/26 (38%)
		TM helix 3	141..171	CDD:320218	11/29 (38%)
		TM helix 4	183..205	CDD:320218	8/21 (38%)
		TM helix 5	230..259	CDD:320218	5/29 (17%)
		TM helix 6	274..304	CDD:320218	15/29 (52%)
		TM helix 7	316..341	CDD:320218	11/24 (46%)