Protein Alignment AstA-R1 and ackr3a

DIOPT Version :10

• Sequence 1: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Sequence 2: XP_005167578.1
• Gene: ackr3a / 100000764
• ZFINID: ZDB-GENE-070301-5
• Length: 403
• Species: Danio rerio
• Alignment Length: 382
• Identity: 99/382 - (25%)
• Similarity: 166/382 - (43%)
• Gaps: 60/382 - (15%)

  Fly    18 WPKASWGATGNGSIISVSNSSGNNYAFTS-----------EHTDHSDHNANDSMEYDAESV---- 67
            |...:...:..|.:..:.:||.|.....|           |..:.:|.| |:|...:|:..
Zfish     6 WINIAHSTSIKGKMTEIQSSSPNEKLGLSASELTEFFAMWEELNFTDSN-NNSSRVEAQMCPASF 69

  Fly    68 ---ALERIVSTIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVP 129
               ||...:.|:    :..|...||..|.||:.|.:.:|:....|::.|:||||:|:     ||.
Zfish    70 NRSALLNAMCTL----YAFIFVVGLAANALVVWVNMRSQRHYHETHMYILNLAVADL-----CVV 125

  Fly   130 FTATDYVLP-----EWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTER 189
            .|...:|..     .|.||...||....:..|....|::.|..||.||:|:||. ...:|.|..|
Zfish   126 ATLPVWVSSLAQGGHWAFGQAACKLTHLLFSVNLFASIFFLTCMSVDRYLSVVR-FREISHRRGR 189

  Fly   190 NATLAIMCA--WITIVTTAIP-VALSHSVRIYQYHGNAGTAC--VFSTEEEIWSLVGFQVSFFLS 249
            ... .::||  |:..:..::| .....||:....|   .|.|  |:..:..:..:||.|:||.:.
Zfish   190 QVR-RLVCAITWLLALFASVPDTYFLRSVKSQYSH---VTLCLPVYPEDNPLQWMVGIQLSFVVL 250

  Fly   250 SYVAPLTLICFLYMGMLARLWKSAPGCKPS--AESRKGKRRVTRMVVVVVLAFAICWLPIHVILV 312
            .:..|..:|...| .:||....|.....||  .:.|...::|..|.:||.:|   ||.|.|.:|:
Zfish   251 GFAIPFPIIAVSY-ALLANTLASTSTHSPSNGDQDRSVSKKVILMYIVVFIA---CWAPYHAVLL 311

  Fly   313 LKALNLYG------GSHLSVIIQI-ISHVVAYTNSCINPILYAFLSDNFR----KAF 358
            ..||.:.|      .|...:.:.: ::..::..:.|:||::|:|...::|    |||
Zfish   312 ADALAMLGVLPLGCSSENGLFVALHLTQCLSLLHCCVNPVVYSFAHRHYRYDLMKAF 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstA-R1	NP_524700.1	7tmA_AstA_R_insect	75..358	CDD:320224	83/305 (27%)
		TM helix 1	76..102	CDD:320224	7/25 (28%)
		TM helix 2	109..135	CDD:320224	10/25 (40%)
		TM helix 3	147..177	CDD:320224	10/29 (34%)
		TM helix 4	189..209	CDD:320224	5/22 (23%)
		TM helix 5	239..268	CDD:320224	9/28 (32%)
		TM helix 6	284..314	CDD:320224	10/29 (34%)
		TM helix 7	326..351	CDD:320224	5/25 (20%)
ackr3a	XP_005167578.1	7tm_GPCRs	77..364	CDD:475119	82/304 (27%)
		TM helix 1	78..102	CDD:410628	8/27 (30%)
		TM helix 2	111..132	CDD:410628	9/25 (36%)
		TM helix 3	149..171	CDD:410628	5/21 (24%)
		TM helix 4	194..210	CDD:410628	3/15 (20%)
		TM helix 5	241..264	CDD:410628	8/23 (35%)
		TM helix 6	289..311	CDD:410628	9/24 (38%)
		TM helix 7	332..357	CDD:410628	5/24 (21%)