DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vih and UBE2E2

DIOPT Version :9

Sequence 1:	NP_648582.1	Gene:	vih / 44118	FlyBaseID:	FBgn0264848	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001357154.1	Gene:	UBE2E2 / 7325	HGNCID:	12478	Length:	201	Species:	Homo sapiens

Alignment Length:	177	Identity:	64/177 - (36%)
Similarity:	86/177 - (48%)	Gaps:	20/177 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AQNI--SPEQSGGAGGGGSKHS-------DDSMPVKDNHAVS-----------KRLHKELMNLMM 46
            ||.:  ||..|||:..|..:.|       :...|.|....:|           ||:.|||..:.:
Human     5 AQRVDDSPSTSGGSSDGDQRESVQQEPEREQVQPKKKEGKISSKTAAKLSTSAKRIQKELAEITL 69

  Fly    47 ANERGISAFPDGENIFKWVGTIAGPRNTVYSGQTYRLSLDFPNSYPYAAPVVKFLTSCFHPNVDL 111
            ......||.|.|:||::|..||.||..:||.|..:.|.:.|...||:..|.|.|.|..:|.|::.
Human    70 DPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINS 134

  Fly   112 QGAICLDILKDKWSALYDVRTILLSIQSLLGEPNNESPLNAQAAMMW 158
            ||.||||||||.||....:..:||||.|||.:.|...||....|..:
Human   135 QGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQY 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vih	NP_648582.1	COG5078	31..166	CDD:227410	53/139 (38%)
vih	NP_648582.1	UQ_con	36..172	CDD:278603	51/123 (41%)
UBE2E2	NP_001357154.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55		12/49 (24%)
UBE2E2	NP_001357154.1	UQ_con	59..196	CDD:395127	51/123 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53976
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920