DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vih and UBE2A

DIOPT Version :9

Sequence 1:	NP_648582.1	Gene:	vih / 44118	FlyBaseID:	FBgn0264848	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_003327.2	Gene:	UBE2A / 7319	HGNCID:	12472	Length:	152	Species:	Homo sapiens

Alignment Length:	141	Identity:	61/141 - (43%)
Similarity:	86/141 - (60%)	Gaps:	1/141 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 KRLHKELMNLMMANERGISAFPDGENIFKWVGTIAGPRNTVYSGQTYRLSLDFPNSYPYAAPVVK 99
            :||.::...|......|:|..|...||..|...|.||..|.:...|::|:::|...||...|.|:
Human     7 RRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVR 71

  Fly   100 FLTSCFHPNVDLQGAICLDILKDKWSALYDVRTILLSIQSLLGEPNNESPLNAQAAMMWNDQK-E 163
            |::..|||||...|:||||||:::||..|||.:||.||||||.|||..||.|:|||.::.:.| |
Human    72 FVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKRE 136

  Fly   164 YKKYLDAFYEK 174
            |:|.:.|..|:
Human   137 YEKRVSAIVEQ 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vih	NP_648582.1	COG5078	31..166	CDD:227410	58/131 (44%)
vih	NP_648582.1	UQ_con	36..172	CDD:278603	60/136 (44%)
UBE2A	NP_003327.2	UQ_con	8..145	CDD:395127	60/136 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910