DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vih and UBE2D4

DIOPT Version :9

Sequence 1:	NP_648582.1	Gene:	vih / 44118	FlyBaseID:	FBgn0264848	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	XP_024302563.1	Gene:	UBE2D4 / 51619	HGNCID:	21647	Length:	192	Species:	Homo sapiens

Alignment Length:	164	Identity:	58/164 - (35%)
Similarity:	87/164 - (53%)	Gaps:	5/164 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AGGGGSKHSDDSMPVKDNHAVSKRLHKELMNLMMANERGISAFPDGENIFKWVGTIAGPRNTVYS 77
            |.|..|.........|:..|    .|.||.:|........||.|.|:::|.|..||.||.::.|.
Human    31 ASGEASGSLQSWQKAKEKQA----CHLELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQ 91

  Fly    78 GQTYRLSLDFPNSYPYAAPVVKFLTSCFHPNVDLQGAICLDILKDKWSALYDVRTILLSIQSLLG 142
            |..:.|::.||..||:..|.|.|.|..:|||::..|:||||||:.:||....|..:||||.|||.
Human    92 GGVFFLTIHFPTDYPFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLC 156

  Fly   143 EPNNESPLNAQAAMMWN-DQKEYKKYLDAFYEKH 175
            :||.:.||..:.|..:. |:::|.:....:.:|:
Human   157 DPNPDDPLVPEIAHTYKADREKYNRLAREWTQKY 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vih	NP_648582.1	COG5078	31..166	CDD:227410	53/135 (39%)
vih	NP_648582.1	UQ_con	36..172	CDD:278603	52/136 (38%)
UBE2D4	XP_024302563.1	UBCc	54..191	CDD:320784	52/137 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53976
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920