DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bgm and FAA2

DIOPT Version :9

Sequence 1:	NP_001285923.1	Gene:	bgm / 44117	FlyBaseID:	FBgn0027348	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_010931.3	Gene:	FAA2 / 856734	SGDID:	S000000817	Length:	744	Species:	Saccharomyces cerevisiae

Alignment Length:	749	Identity:	168/749 - (22%)
Similarity:	305/749 - (40%)	Gaps:	136/749 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IDALYNR-PGPNRLRQADAYRTTNRQDAVKI----------RMAKDGIGAEEPISVPGLLKRTVN 57
            |:.||:: |    |.....|:|..::.||.|          .:.:..:.:|..:|......||..
Yeast    36 IEELYSQLP----LTSYPRYKTFLKKQAVAISNPDNEAGFSSIYRSSLSSENLVSCVDKNLRTAY 96

  Fly    58 NYGDYPALR---------------TKNGKNGYHTVTYKQYEQKVHQVAKAFIKL-------GLEE 100
            ::..:.|.|               |...:..:...:|....::.|.:....:.|       .||.
Yeast    97 DHFMFSARRWPQRDCLGSRPIDKATGTWEETFRFESYSTVSKRCHNIGSGILSLVNTKRKRPLEA 161

  Fly   101 H-HSVGVLAFNCAEWFYSAMGAIHARGII-AGIYTTNSADAVQHVLESSHAQIVV---------- 153
            : ..|.:|:.|..||..:.: |..|..:. ..:|.|...:..:::|..:.|.|::
Yeast   162 NDFVVAILSHNNPEWILTDL-ACQAYSLTNTALYETLGPNTSEYILNLTEAPILIFAKSNMYHVL 225

  Fly   154 --VDDAK------QMDKIHAIRDKLPKLKAAIQIQEPYSPYLKKEDGYYRWSEIESMN------- 203
              |.|.|      .||::  ..|:|..|..::...:..|  |.::..::...::|.:.
Yeast   226 KMVPDMKFVNTLVCMDEL--THDELRMLNESLLPVKCNS--LNEKITFFSLEQVEQVGCFNKIPA 286

  Fly   204 VSDVEDQYMTRLENVAINECCCLVYTSGTVGMPKGVMLSHDNITFDVRGIVKAMDRVVVGAES-- 266
            :....|...|            :.:||||.|:||||.:||.||   ..||..|.....:..:.
Yeast   287 IPPTPDSLYT------------ISFTSGTTGLPKGVEMSHRNI---ASGIAFAFSTFRIPPDKRN 336

  Fly   267 ----IVSYLPLSHVAAQTVDIYTCAFVAGCIWFADKDALKGTLVKSLQDARPTRFMGVPRVYEKF 327
                .:.:|||:|:..:.|..|..|...|..:....|..  .||:.|:..:|.....|||:..:|
Yeast   337 QQLYDMCFLPLAHIFERMVIAYDLAIGFGIGFLHKPDPT--VLVEDLKILKPYAVALVPRILTRF 399

  Fly   328 QERMVAVASSSGSLKKMLASWAKGITLKHYMVSQGKSSGGFRYKIAKSLIMSKVKQALGFDRVLT 392
             |..:..|....::::.:|:.........:....|.......:.:...:::.|::.:||......
Yeast   400 -EAGIKNALDKSTVQRNVANTILDSKSARFTARGGPDKSIMNFLVYHRVLIDKIRDSLGLSNNSF 463

  Fly   393 LASAAAPMSPETKKYFLS-LDLKIVDAFGMSET-AGCHTICLPD----------SVGLNTIGKTL 445
            :.:.:||:|.:|..:..| ||:.|...:|::|| ||   :||.:          ::|::.
Yeast   464 IITGSAPISKDTLLFLRSALDIGIRQGYGLTETFAG---VCLSEPFEKDVGSCGAIGISA----- 520

  Fly   446 PGCESKFI-----NKDANGHGELCIRGRHVFMGYIDNKEKTEESLDDDCWLHSGDLGFVDDKGYV 505
             .|..|.:     :.|.:..|||.|||..||..|..|..:|.:::|.|.|..:||:.|:|.||.:
Yeast   521 -ECRLKSVPEMGYHADKDLKGELQIRGPQVFERYFKNPNETSKAVDQDGWFSTGDVAFIDGKGRI 584

  Fly   506 SLTGRSKEIIITAGGENIPPVHIENTIKKELDAISNAFLVGEQRKYLTVLITLKTEVDKDSGEPL 570
            |:..|.|.....|.||.|.|..|||........|:..|:.|:..|  |.|:.: ..||.|:.:|:
Yeast   585 SVIDRVKNFFKLAHGEYIAPEKIENIYLSSCPYITQIFVFGDPLK--TFLVGI-VGVDVDAAQPI 646

  Fly   571 DELSH-ESSVWVKSLGVEHKTVSDILAAGPCPKVWKSIEDAIKRANK--QSISNAQKVQKFTILP 632
            ....| |...|.|.:.||:...:.           |..::.:.:.||  ..:...:|:....:..
Yeast   647 LAAKHPEVKTWTKEVLVENLNRNK-----------KLRKEFLNKINKCTDGLQGFEKLHNIKVGL 700

  Fly   633 HDFSIPTGELGPTLKVKRNVVSKMYADEIEKLYA 666
            ...::....:.||.|:||...||.:.|.:::|||
Yeast   701 EPLTLEDDVVTPTFKIKRAKASKFFKDTLDQLYA 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bgm	NP_001285923.1	FAA1	32..666	CDD:223953	157/718 (22%)
bgm	NP_001285923.1	ACSBG_like	69..665	CDD:213299	148/655 (23%)
FAA2	NP_010931.3	LC-FACS_euk	126..734	CDD:341250	149/653 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810