DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bgm and AAE16

DIOPT Version :9

Sequence 1:	NP_001285923.1	Gene:	bgm / 44117	FlyBaseID:	FBgn0027348	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_189021.2	Gene:	AAE16 / 821961	AraportID:	AT3G23790	Length:	722	Species:	Arabidopsis thaliana

Alignment Length:	722	Identity:	157/722 - (21%)
Similarity:	299/722 - (41%)	Gaps:	171/722 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 IGAEEPISVPGLLKRTVNNYGDYPALRTKNGKNGYH----TVTYKQYEQKVHQVAKAFIKLGLEE 100
            :.:.|..|||.:.:.:|..|||..|:     .:.||    |.||:|.||::....:....:|::.
plant    75 LSSNEWKSVPDIWRSSVEKYGDRVAV-----VDPYHDPPSTFTYRQLEQEILDFVEGLRVVGVKA 134

  Fly   101 HHSVGVLAFNCAEWFYSAMG--AIHARGIIAGIYTTNSADAVQHVLE---SSHAQIVVVDDAKQM 160
            ...:.:.|.|...|..:..|  |..|..::.|     |..:|:.:|:   .|.:..:|||:.:..
plant   135 DEKIALFADNSCRWLVADQGIMATGAVNVVRG-----SRSSVEELLQIYCHSESVALVVDNPEFF 194

  Fly   161 DKI-HAIRDK-LPKL-------KAAIQIQEPYSPYLKKEDGYYRWSEIESM------NVSDVEDQ 210
            ::| .:...| .||.       |:::.....::|       .|.::||:..      ..:...|.
plant   195 NRIAESFSYKAAPKFVILLWGEKSSLVTAGRHTP-------VYSYNEIKKFGQERRAKFARSNDS 252

  Fly   211 YMTRLENVAINECCCLVYTSGTVGMPKGVMLSHDNITFDVRGIVKAMDRVVVGA-ESIVSYLPLS 274
            .....|.:..::...::|||||.|.||||||:|.|:...:|.:   .|.|...| |..:|.||..
plant   253 GKYEYEYIDPDDIATIMYTSGTTGNPKGVMLTHQNLLHQIRNL---SDFVPAEAGERFLSMLPSW 314

  Fly   275 HVAAQTVD--IYTCAFVAGCIWFADKDALKGTLVKSLQD----ARPTRFMGVPRVYEKFQERMVA 333
            |...:..:  |:||..           ..|.|.::.|:|    .:|...:.||.|||.....:..
plant   315 HAYERACEYFIFTCGV-----------EQKYTSIRFLKDDLKRYQPHYLISVPLVYETLYSGIQK 368

  Fly   334 VASSSGSLKKMLASWAKGITLKH--------------------YMVS-----QGKSSGGF---RY 370
            ..|:|...:|.||.....::|.:                    |:||     ..:....|   .:
plant   369 QISASSPARKFLALTLIKVSLAYTEMKRVYEGLCLTKNQKPPMYIVSLVDWLWARVVAFFLWPLH 433

  Fly   371 KIAKSLIMSKVKQALGFDRVLTLASAAAPMSPETKKYFLSLDLKIVDAFGMSETA--------GC 427
            .:|:.|:..|::.::|..:.......:.||  ...|:|.::.:.:.:.:|::||:        .|
plant   434 MLAEKLVHRKIRSSIGITKAGVSGGGSLPM--HVDKFFEAIGVNVQNGYGLTETSPVVSARRLRC 496

  Fly   428 HTICLPDSVGLNTIGKTLPGCESKFINKDA------NGHGELCIRGRHVFMGYIDNKEKTEESLD 486
            :.        |.::|..:...|.|.::.:.      ...|.:.:||..|..||..|...|::.:|
plant   497 NV--------LGSVGHPIKDTEFKIVDHETGTVLPPGSKGIVKVRGPPVMKGYYKNPLATKQVID 553

  Fly   487 DDCWLHSGDLGFVDDK----------GYVSLTGRSKEIIITAGGENIPPVHIENTIKKELDAISN 541
            ||.|.::||:|::..:          |.:.|.||:|:.|:.:.|||:.|:.||....:. :.|..
plant   554 DDGWFNTGDMGWITPQHSTGRSRSCGGVIVLEGRAKDTIVLSTGENVEPLEIEEAAMRS-NLIQQ 617

  Fly   542 AFLVGEQRKYLTVLITLKTEVDKDSGEPLDELSHESSVWVKSLGVEHKTVSDILAAGPCPKVWKS 606
            ..::|:.::.|..::....|.                                 |.|...:....
plant   618 IVVIGQDQRRLGAIVIPNKEA---------------------------------AEGAAKQKISP 649

  Fly   607 IEDAIKRANKQSISNA--QKVQKFT-----------ILPHDFSIPTGELGPTLKVKRNVVSKMYA 658
            ::..:...:|::|::.  ::::|:|           |:...|:|..|.:.||:|::|:.|...|.
plant   650 VDSEVNELSKETITSMVYEELRKWTSQCSFQVGPVLIVDEPFTIDNGLMTPTMKIRRDKVVDQYK 714

  Fly   659 DEIEKLY 665
            :|||:||
plant   715 NEIERLY 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bgm	NP_001285923.1	FAA1	32..666	CDD:223953	157/722 (22%)
bgm	NP_001285923.1	ACSBG_like	69..665	CDD:213299	146/691 (21%)
AAE16	NP_189021.2	LC_FACS_like	106..709	CDD:341295	139/672 (21%)
AAE16	NP_189021.2	PTZ00237	<232..>281	CDD:240325	12/48 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D806831at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.780