Protein Alignment bgm and ACSBG2

DIOPT Version :10

• Sequence 1: NP_524698.1
• Gene: bgm / 44117
• FlyBaseID: FBgn0027348
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_112186.3
• Gene: ACSBG2 / 81616
• HGNCID: 24174
• Length: 666
• Species: Homo sapiens
• Alignment Length: 647
• Identity: 277/647 - (42%)
• Similarity: 429/647 - (66%)
• Gaps: 15/647 - (2%)

  Fly    24 TTNRQDAVKIRMAKDGIGAEEPISVPGLLKRTVNNYGDYPALRTKNGKNGYHTVTYKQYEQKVHQ 88
            ||.|...|.:|::|.|.|.|.|:::|...:.:||.:|.||||.:||||. :..:.:.||.:...:
Human    29 TTCRDGEVLLRLSKHGPGHETPMTIPEFFRESVNRFGTYPALASKNGKK-WEILNFNQYYEACRK 92

  Fly    89 VAKAFIKLGLEEHHSVGVLAFNCAEWFYSAMGAIHARGIIAGIYTTNSADAVQHVLESSHAQIVV 153
            .||:.||||||..|.||:|.||.||||.:|:|||.|.|:..|||.||||:..|:|:..:...|::
Human    93 AAKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILL 157

  Fly   154 VDDAKQMDKIHAI-RDKLPKLKAAIQIQEPYSPYLKKEDGYYRWSEIESMNVSDVEDQYMTRLEN 217
            |::.:|:.||.:| :..|..|||.||.:.|    :||.:..|.|.:...:..|..:.|....:|:
Human   158 VENDQQLQKILSIPQSSLEPLKAIIQYRLP----MKKNNNLYSWDDFMELGRSIPDTQLEQVIES 218

  Fly   218 VAINECCCLVYTSGTVGMPKGVMLSHDNITFDVRGIVKAMDRVVVGAESIVSYLPLSHVAAQTVD 282
            ...|:|..|:|||||.|:||||||||||||: :.|.|....::....|::||||||||:|||.:|
Human   219 QKANQCAVLIYTSGTTGIPKGVMLSHDNITW-IAGAVTKDFKLTDKHETVVSYLPLSHIAAQMMD 282

  Fly   283 IYTCAFVAGCIWFADKDALKGTLVKSLQDARPTRFMGVPRVYEKFQERMVAVASSSGSLKKMLAS 347
            |:....:....:||..||||||||.:|::.:||.|:|||:::||..|.:...::.|..|||....
Human   283 IWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFV 347

  Fly   348 WAKGITLKHYMVSQGKSSGGFR----YKIAKSLIMSKVKQALGFDRVLTLASAAAPMSPETKKYF 408
            ||:.|..|   |:..|..|.:.    |::||:|:.||||.:||.|...:..|..||::.||.::|
Human   348 WARNIGFK---VNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFF 409

  Fly   409 LSLDLKIVDAFGMSETAGCHTICLPDSVGLNTIGKTLPGCESKFINKDANGHGELCIRGRHVFMG 473
            ||||:.|.:.:|:||::|.|||...::..|.:.||.|.||::....::.:|.||:|:.|||:|||
Human   410 LSLDIPIGELYGLSESSGPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEICLWGRHIFMG 474

  Fly   474 YIDNKEKTEESLDDDCWLHSGDLGFVDDKGYVSLTGRSKEIIITAGGENIPPVHIENTIKKELDA 538
            |::::.:|.|::||:.||||||||.:|..|::.:||..|||:|||||||:||:.:|..:||::..
Human   475 YLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPVETLVKKKIPI 539

  Fly   539 ISNAFLVGEQRKYLTVLITLKTEVDKDSGEPLDELSHESSVWVKSLGVEHKTVSDILAAGPCPKV 603
            ||||.|||::.|:|::|:|||.|:::.||||||:|:.|:..:.:.||.:..||::|:.... |.|
Human   540 ISNAMLVGDKLKFLSMLLTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTVTEIVKQQD-PLV 603

  Fly   604 WKSIEDAIKRANKQSISNAQKVQKFTILPHDFSIPTGELGPTLKVKRNVVSKMYADEIEKLY 665
            :|:|:..|...|:::::|||:::|:.||..||||..|||||.:|:||:.|::.|..:|:.:|
Human   604 YKAIQQGINAVNQEAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQIDHMY 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bgm	NP_524698.1	ACSBG_like	69..665	CDD:341256	257/600 (43%)
ACSBG2	NP_112186.3	ACSBG_like	73..665	CDD:341256	258/601 (43%)