DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bgm and acsl3b

DIOPT Version :9

Sequence 1:	NP_001285923.1	Gene:	bgm / 44117	FlyBaseID:	FBgn0027348	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001139404.1	Gene:	acsl3b / 559656	ZFINID:	ZDB-GENE-030131-492	Length:	711	Species:	Danio rerio

Alignment Length:	734	Identity:	159/734 - (21%)
Similarity:	292/734 - (39%)	Gaps:	156/734 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NRPGPNRLRQADAYRTTNRQDAVKIRMAK---DGIGAEEPISVPGLLKRTVNNYGDYPALRTK-- 68
            |..||        ||..|.|    :::|.   :|:...:.:     .:..|.::.:...|.|:
Zfish    54 NPAGP--------YRAVNSQ----LKLASLLHEGVDTLDKV-----FEYAVVHFPERDCLGTREL 101

  Fly    69 ---------NGK-------NGYHTVTYKQYEQKVHQVAKAFIKLGLEEHHSVGVLAFNCAEWFYS 117
                     |||       ..|:.::|:.......:.......||.:...::.:.....|||..:
Zfish   102 LSEEDEIQPNGKVFKKVILGDYNWLSYQDTFHLAQRFGSGLAALGQKPLCNIAIFCETRAEWVIA 166

  Fly   118 AMGAIHARGIIAGIYTTNSADAVQHVLESSHAQIVVVDDAKQMDKIHAIRDKLPKLKAAIQIQ-E 181
            |.........:..:|:|....|:.|.|..:....:|........::.||..::|:||..|.:. :
Zfish   167 AQACFMYNFPLVTLYSTLGGSAIAHGLNETEVTHIVTSKDLLQSRLKAILLEVPRLKHIIVVDTK 231

  Fly   182 PYS-PYLKKEDGYYRWSEIESMNVSDVEDQYMTRLENVAINECCCLVYTSGTVGMPKGVMLSHDN 245
            |.| |.|.:....:..:.::.:. |..|:..::|.:.|. ::...::||||:.|:|||||:||.|
Zfish   232 PTSWPDLPRGIMVHNMAAVQELG-SKPENIMVSRRQPVP-SDIAVIMYTSGSTGIPKGVMISHSN 294

  Fly   246 ITFDVRGIVKAMDRVVVGAESIVSYLPLSHVAAQTVDIYTCAFVAGC-IWFADKDAL--KGTLVK 307
            |...:.|:.:.:..:... ::.:.||||:||...:.::...:.  || |.::....|  :.:.:|
Zfish   295 IIAGITGMAERIPNLDEN-DTYIGYLPLAHVLELSAELVCVSH--GCRIGYSSPQTLADQSSKIK 356

  Fly   308 --SLQDA---RPTRFMGVPRVYEKFQERMVAVASSSGSLKKMLASWAKGITLKHYMVSQGKSSGG 367
              |..|.   :||....||.:.::..:.::.......|::|.|...|       |.....:.|.|
Zfish   357 KGSKGDTSVLKPTLMAAVPEIMDRIYKNVMTKVEEMSSVQKTLFVLA-------YNYKMEQISKG 414

  Fly   368 FRYKIAKSLIMSKVKQALGFDRVLTLASAAAPMSPETKKYF-LSLDLKIVDAFGMSETAGCHTIC 431
            :...:...|:..||:..|| .....|.|..||:|..|:::. :.....:...:|::||.|..||.
Zfish   415 YTTPLCDRLVFRKVRSLLG-GNTRVLLSGGAPLSAATQRFMNICFCCPVGQGYGLTETCGAGTIS 478

  Fly   432 LPDSVGLNTIGKTLPGCESKFINKD-----------ANGHGELCIRGRHVFMGYIDNKEKTEESL 485
            .........:|..|. | |:.:.||           .|..||:.|.|.:|.|||..|::|..|..
Zfish   479 EMSDYSTGRVGAPLV-C-SEIMLKDWEEGGYFSTDKPNPRGEILIGGPNVTMGYYKNEQKNREDF 541

  Fly   486 DDD----CWLHSGDLGFVDDKGYVSLTGRSKEIIITAGGENIPPVHIENTIKK-----ELDAISN 541
            .:|    .|..:||:|.....|.:.:..|.|:::....||.:....:|..:|.     .:.|.:|
Zfish   542 FEDKNGQRWFCTGDIGEFHPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAVLKNCPLIDNICAYAN 606

  Fly   542 ---AFLVG---EQRKYLTVLITLK------------TEVDKDSGEPLDELSHESSVWVKSLGVEH 588
               ::::|   ..:|.||.|...|            .|::|:
Zfish   607 SDESYVIGFVVPNQKQLTALAGQKGIRGSWEEICNHAEMEKE----------------------- 648

  Fly   589 KTVSDILAAGPCPKVWKSIEDAIKRANKQSISNAQKVQKFTILPHDFSI-------PTGELGPTL 646
                          |.:.|.||       :||.  |:::|.| |....:       .||.:....
Zfish   649 --------------VLRIITDA-------AISG--KLERFEI-PKKICLSAEPWTPETGLVTDAF 689

  Fly   647 KVKRNVVSKMYADEIEKLY 665
            |:||..:...|.|:||::|
Zfish   690 KLKRKELKTHYQDDIERMY 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bgm	NP_001285923.1	FAA1	32..666	CDD:223953	152/711 (21%)
bgm	NP_001285923.1	ACSBG_like	69..665	CDD:213299	146/658 (22%)
acsl3b	NP_001139404.1	PLN02387	43..708	CDD:215217	158/732 (22%)
acsl3b	NP_001139404.1	LC-FACS_euk	121..708	CDD:213293	143/648 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810