DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bgm and acsl1a

DIOPT Version :9

Sequence 1:	NP_001285923.1	Gene:	bgm / 44117	FlyBaseID:	FBgn0027348	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001027007.1	Gene:	acsl1a / 555308	ZFINID:	ZDB-GENE-050809-115	Length:	697	Species:	Danio rerio

Alignment Length:	699	Identity:	182/699 - (26%)
Similarity:	307/699 - (43%)	Gaps:	113/699 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PGPNRLRQA-----DAYRTTNRQDAVKIRMAKDGIGAEEPISVPGLLKRTVNNYGDYPALRTKNG 70
            ||....|::     |.:.|...:||:.:          ....:.||  |..||   .|.|.::..
Zfish    65 PGKEYARRSILMDNDTHMTYYYKDALTL----------YEFFLRGL--RVPNN---GPCLGSRKA 114

  Fly    71 KNGYHTVTYKQYEQKVHQVAKAFIKLGLEEHHS------VGVLAFNCAEWFYSAMGAIHARGIIA 129
            ...|..::||:...:......|.:..|    ||      :|:.|.|..||..|.:.......:..
Zfish   115 GQPYKWLSYKEVADRAEFAGSALLHRG----HSQSGDKYIGIFAQNRPEWTISELACYTYSLVAV 175

  Fly   130 GIYTTNSADAVQHVLESSHAQIVVVDDAKQMDKIHAIRDKLPKLK---AAIQIQEPYSPYLKKED 191
            .:|.|...:|:.:|::.:....::.|.|   ||...|.|.:...|   ..|.|.|.:...|..:.
Zfish   176 PLYDTLGTEAISYVIDKASITTIICDIA---DKARLILDCVSGRKHSVTTIVIMESFDSELTAQA 237

  Fly   192 -----GYYRWSEIESMNVSDVEDQYMTRLENVAINECCCLVYTSGTVGMPKGVMLSHDNITFDVR 251
                 ......|:|::..::.:.....:.|::|:     :.:||||.|.|||.||:|.|:..:..
Zfish   238 QNCGIDIISLKELEAIGKANHKTPIPPKPEDLAL-----ICFTSGTTGNPKGAMLTHGNVVSNCS 297

  Fly   252 GIVKAMD-RVVVGAESI-VSYLPLSHVAAQTVDIYTCAFVAGCIWFADKDALKGTLVKSLQDARP 314
            ..:|..: ..::....| :|||||:|:..:.|:.......|...:|.....|   |:..|::.:|
Zfish   298 AFIKITEVHCMLNQTDIHISYLPLAHMFERVVEGVLLCHGAKIGYFQGDIRL---LMDDLKNLKP 359

  Fly   315 TRFMGVPRVYEKFQERMVAVASSSGSLKKMLASWA---KGITLKHYMVSQGKSSGGFRYKIAKSL 376
            |.|..|||:..:..:::...|::  .||:.|..:|   |...||..:|.:.        .:...|
Zfish   360 TIFPVVPRLLNRMFDKIFGQANT--PLKRWLLDFATSRKEAELKSGVVRKD--------SMWDKL 414

  Fly   377 IMSKVKQALGFDRVLTLASAAAPMSPETKKYFL--SLDLKIVDAFGMSE-TAGCHTICLPDSVGL 438
            |.|||:.:|| .||..:.:.|||:|| |...||  :|..:..:.:|.:| |||| |:.||.....
Zfish   415 IFSKVQASLG-GRVRLMITGAAPVSP-TVLTFLRAALGCQFYEGYGQTECTAGC-TMSLPGDWTA 476

  Fly   439 NTIGKTLPGCESKFINK------DANGHGELCIRGRHVFMGYIDNKEKTEESLDDDCWLHSGDLG 497
            ..:|..||....|.::.      .|||.||:|::|.:||.||:.:.|:|..::|...|||:||:|
Zfish   477 GHVGAPLPCNFVKLVDVAEMNYFAANGEGEVCVKGPNVFQGYLKDPEQTSGAVDKAGWLHTGDIG 541

  Fly   498 FVDDKGYVSLTGRSKEIIITAGGENIPPVHIENTIKKELDAISNAFLVGEQRKYLTVLITLKTEV 562
            .....|.:.:..|.|.|...|.||.|.|..||| |....|.::..|:.|:..:...|.:.:.
Zfish   542 KWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIEN-IYIRSDPVAQVFVHGDSLQACLVGVVVP--- 602

  Fly   563 DKD--SGEPLDELSHESSVWVKSLGVE--------HKTVSDILAAGPCPKVWKSIEDAIKRANKQ 617
            |.|  .|            |.|:.|:|        .|.|.:.:           :||.|:...:.
Zfish   603 DPDFLPG------------WAKNRGIEGSFNDLCKSKEVKNAI-----------LEDMIQLGKEA 644

  Fly   618 SISNAQKVQKFTILPHDFSIPTGELGPTLKVKRNVVSKMYADEIEKLYA 666
            .:.:.::|:...:....||:..|.|.||||.||..:...:.::|::|||
Zfish   645 GLKSFEQVRDIALHLEMFSVQNGLLTPTLKAKRTELKSRFREQIDQLYA 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bgm	NP_001285923.1	FAA1	32..666	CDD:223953	173/671 (26%)
bgm	NP_001285923.1	ACSBG_like	69..665	CDD:213299	165/633 (26%)
acsl1a	NP_001027007.1	PLN02736	88..695	CDD:178337	177/676 (26%)
acsl1a	NP_001027007.1	LC-FACS_euk	116..692	CDD:213293	165/630 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810