DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bgm and Acsl4

DIOPT Version :9

Sequence 1:	NP_001285923.1	Gene:	bgm / 44117	FlyBaseID:	FBgn0027348	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_997508.1	Gene:	Acsl4 / 50790	MGIID:	1354713	Length:	711	Species:	Mus musculus

Alignment Length:	738	Identity:	169/738 - (22%)
Similarity:	289/738 - (39%)	Gaps:	164/738 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PNRLRQADAYRTTNRQDAVKIRMAKDGIGAEEPISVPG------LLKRTVNNYGDYPALRTK--- 68
            |...:....||:....|::.:            |.:||      |....|..:|...:|.|:
Mouse    50 PTSDKPGSPYRSVTHFDSLAV------------IDIPGADTLDKLFDHAVAKFGKKDSLGTREIL 102

  Fly    69 --------NGK-------NGYHTVTYKQYEQKVHQVAKAFIKLGLEEHHSVGVLAFNCAEWFYSA 118
                    |||       ..|..:.|.:...:|:........|||:..:::.:.....|||..:|
Mouse   103 SEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAA 167

  Fly   119 MGAIHARGIIAGIYTTNSADAVQHVLESSHAQIVVVDDAKQMDKIHAIRDKLPKLKAAIQIQEPY 183
            .........:..:|.|...:||.|.|..|.|..::........|:.|....:..:|..|.:....
Mouse   168 QTCFKYNFPLVTLYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKT 232

  Fly   184 SPYLKKEDGYYRWSEIESMNVSDVEDQYMTRLENVAI-------NECCCLVYTSGTVGMPKGVML 241
            ....:..:|.    ||.||  ..|| :...:.||:::       ::...::||||:.|.|||||:
Mouse   233 INRAEYPEGL----EIHSM--QSVE-ELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMM 290

  Fly   242 SHDNITFDVRGIVKAMDRV--VVGAESIVSYLPLSHVAAQTVDIYTCAFVAGC-------IWFAD 297
            .|.|:   :.|:....:|:  :...::.:.||||:||...|.:| :| |..||       :..:|
Mouse   291 HHSNL---IAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SC-FTYGCRIGYSSPLTLSD 350

  Fly   298 -----KDALKG--TLVKSLQDARPTRFMGVPRVYEKFQERMVAVASSSGSLKKMLASWAKGITLK 355
                 |...||  |::|      ||....||.:.::..:.:::.......::|.|....     .
Mouse   351 QSSKIKKGSKGDCTVLK------PTLMAAVPEIMDRIYKNVMSKVQEMNYVQKTLFKIG-----Y 404

  Fly   356 HYMVSQGKSSGGFRYKIAKSLIMSKVKQALGFDRVLTLASAAAPMSPETKKYF-LSLDLKIVDAF 419
            .|.:.|.|.  |:...:...::..|||..|| ..|..:.|..||:||:|.::. :.....|...:
Mouse   405 DYKLEQIKK--GYDAPLCNLILFKKVKALLG-GNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGY 466

  Fly   420 GMSETAGCHTICLPDSVGLNTIGKTLPGCESKF---------INKDANGHGELCIRGRHVFMGYI 475
            |::|:.|..|:..........:|..|..||.|.         ::...|..||:.|.|:::.|||.
Mouse   467 GLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYF 531

  Fly   476 DNKEKTEESLDDDC-------WLHSGDLGFVDDKGYVSLTGRSKEIIITAGGENIPPVHIENTIK 533
            .|:|||.|   |.|       |..:||:|.....|.:.:..|.|:::....||.:....:|..:
Mouse   532 KNEEKTAE---DYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAAL- 592

  Fly   534 KELDAISN-------------AFLVGEQRKYLTVLITLKTEVDKDSGEPLDELSHESSVWVKSLG 585
            |....|.|             :|:|..|:| ||:|...|                         |
Mouse   593 KNCPLIDNICAFAKSDQSYVISFVVPNQKK-LTLLAQQK-------------------------G 631

  Fly   586 VEHKTVSDILAAGPC--PKVWKSIEDAIKRANKQSISNAQKVQKFTI------LPHDFSIPTGEL 642
            ||...|.  :...|.  .::.|.|.:|         :||.|:::|.|      .|..::..||.:
Mouse   632 VEGSWVD--ICNNPAMEAEILKEIREA---------ANAMKLERFEIPIKVRLSPEPWTPETGLV 685

  Fly   643 GPTLKVKRNVVSKMYADEIEKLY 665
            ....|:||..:...|..:||::|
Mouse   686 TDAFKLKRKELKNHYLKDIERMY 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bgm	NP_001285923.1	FAA1	32..666	CDD:223953	165/719 (23%)
bgm	NP_001285923.1	ACSBG_like	69..665	CDD:213299	156/663 (24%)
Acsl4	NP_997508.1	LC_FACS_euk1	121..696	CDD:341294	150/641 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900