DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bgm and Acsl3

DIOPT Version :9

Sequence 1:	NP_001285923.1	Gene:	bgm / 44117	FlyBaseID:	FBgn0027348	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_476448.1	Gene:	Acsl3 / 114024	RGDID:	70552	Length:	720	Species:	Rattus norvegicus

Alignment Length:	738	Identity:	158/738 - (21%)
Similarity:	295/738 - (39%)	Gaps:	157/738 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PNRLRQA-------DAYRTTNRQDAVKIRMAKDGIGAEEPISVPG------LLKRTVNNYGDYPA 64
            ||.::..       .|||:.|         :.||:.:   :..||      :.....|.:.|...
  Rat    52 PNHIKAKPVSSKPDSAYRSVN---------SMDGLAS---VLYPGCDTLDKVFMYAKNKFKDKRL 104

  Fly    65 LRTK-----------NGK-------NGYHTVTYKQYEQKVHQVAKAFIKLGLEEHHSVGVLAFNC 111
            |.|:           |||       ..|:.::|:....:..........||.:...::.:.....
  Rat   105 LGTREILNEEDEIQPNGKVFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETR 169

  Fly   112 AEWFYSAMGAIHARGIIAGIYTTNSADAVQHVLESSHAQIVVVDDAKQMDKIHAIRDKLPKLKAA 176
            |||..:|.........:..:|.|....|:.|.|..:....::........|:..|...:|:|:..
  Rat   170 AEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHI 234

  Fly   177 IQIQEPYSPYLKKEDGY-YRWSE------------IESMNV-SDVEDQYMTR--LENVAINECCC 225
            |.:           ||. ..|||            ::::.| :||:.:..::  ..::|:
  Rat   235 ITV-----------DGKPPTWSEFPKGVIVHTMAAVQALGVKADVDKKAHSKPLPSDIAV----- 283

  Fly   226 LVYTSGTVGMPKGVMLSHDNITFDVRGIVKAMDRVVVGAESI-VSYLPLSHVAAQTVDIYTCAFV 289
            ::||||:.|:|||||:||.||...:.|:.:.:.|  :|.|.: :.||||:||...:.::...:.
  Rat   284 IMYTSGSTGIPKGVMISHSNIIASITGMARRIPR--LGEEDVYIGYLPLAHVLELSAELVCLSH- 345

  Fly   290 AGC-IWFADKDAL--KGTLVK--SLQDA---RPTRFMGVPRVYEKFQERMVAVASSSGSLKKMLA 346
             || |.::....|  :.:.:|  |..|.   :||....||.:.::..:.::...:...:.::.|
  Rat   346 -GCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNL- 408

  Fly   347 SWAKGITLKHYMVSQGKSSGGFRYKIAKSLIMSKVKQALGFDRVLTLASAAAPMSPETKKYF-LS 410
             :......|...:|:|.|:     .:....:...|::.|| ..:..|....||:|..|:::. :.
  Rat   409 -FILAYNYKMEQISKGCST-----PLCDRFVFRNVRRLLG-GNIRVLLCGGAPLSATTQRFMNIC 466

  Fly   411 LDLKIVDAFGMSETAGCHTICLPDSVGLNTIGKTLPGCESKFINKDANGH---------GELCIR 466
            ....:...:|::|:.|..||..........:|..|..||.|..|.:..|:         ||:.|.
  Rat   467 FCCPVGQGYGLTESTGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIG 531

  Fly   467 GRHVFMGYIDNKEKTEESLDDD----CWLHSGDLGFVDDKGYVSLTGRSKEIIITAGGENIPPVH 527
            |::|.|||..|:.||:....:|    .||.:||:|..|..|.:.:..|.|:::....||.:....
  Rat   532 GQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGK 596

  Fly   528 IENTIKKELDAISN-------------AFLVGEQRKYLTVLITLKTEVDKDSG--EPLDELSHES 577
            :|..: |.|..|.|             .|:|..|::.        ||:.:..|  ...:||.:.|
  Rat   597 VEAAL-KNLPLIDNICAYANSYHSYVIGFVVPNQKEL--------TELARTKGFNGTWEELCNSS 652

  Fly   578 SVWVKSLGVEHKTVSDILAAGPCPKVWKSIEDAIKRANKQSISNAQKVQKFTILPHDFSIPTGEL 642
            .       :|:             :|.|.:.:|   |...|:...:...|..:.|..::..||.:
  Rat   653 E-------MEN-------------EVLKVLSEA---AISASLEKFEIPLKIRLSPDPWTPETGLV 694

  Fly   643 GPTLKVKRNVVSKMYADEIEKLY 665
            ....|:||..:...|..:||::|
  Rat   695 TDAFKLKRKELKTHYQADIERMY 717

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bgm	NP_001285923.1	FAA1	32..666	CDD:223953	152/712 (21%)
bgm	NP_001285923.1	ACSBG_like	69..665	CDD:213299	143/656 (22%)
Acsl3	NP_476448.1	PLN02387	30..717	CDD:215217	157/736 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810