DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bgm and Acsl4

DIOPT Version :9

Sequence 1:	NP_001285923.1	Gene:	bgm / 44117	FlyBaseID:	FBgn0027348	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	XP_006257376.1	Gene:	Acsl4 / 113976	RGDID:	69401	Length:	711	Species:	Rattus norvegicus

Alignment Length:	735	Identity:	170/735 - (23%)
Similarity:	292/735 - (39%)	Gaps:	158/735 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PNRLRQADAYRTTNRQDAVKIRMAKDGIGAEEPISVPG------LLKRTVNNYGDYPALRTK--- 68
            |...:....||:....|::.:            |.:||      |....|..:|...:|.|:
  Rat    50 PTSDKPGSPYRSVTHFDSLAV------------IDIPGADTLDKLFDHAVAKFGKKDSLGTREIL 102

  Fly    69 --------NGK-------NGYHTVTYKQYEQKVHQVAKAFIKLGLEEHHSVGVLAFNCAEWFYSA 118
                    |||       ..|..:.|.:...:|:........|||:..:::.:.....|||..:|
  Rat   103 SEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAA 167

  Fly   119 MGAIHARGIIAGIYTTNSADAVQHVLESSHAQIVVVDDAKQMDKIHAIRDKLPKLKAAIQIQEPY 183
            .........:..:|.|...:||.|.|..|.|..::........|:.|....:..:|..|.:....
  Rat   168 QTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKAALLDINCVKHIIYVDNKT 232

  Fly   184 SPYLKKEDGYYRWSEIESMNVSDVEDQYMTRLENVAI-------NECCCLVYTSGTVGMPKGVML 241
            ....:..:|.    ||.||  ..|| :..::.||.:|       ::...::||||:.|.|||||:
  Rat   233 INRAEYPEGL----EIHSM--QSVE-ELGSKPENSSIPPSRPTPSDMAIVMYTSGSTGRPKGVMM 290

  Fly   242 SHDNITFDVRGIVKAMDRV--VVGAESIVSYLPLSHVAAQTVDIYTCAFVAGC-------IWFAD 297
            .|.|:   :.|:....:|:  :...::.:.||||:||...|.:| :| |..||       :..:|
  Rat   291 HHSNL---IAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SC-FTYGCRIGYSSPLTLSD 350

  Fly   298 -----KDALKG--TLVKSLQDARPTRFMGVPRVYEKFQERMVAVASSSGSLKKMLASWAKGITLK 355
                 |...||  |::|      ||....||.:.::..:.:::.......::|.|....     .
  Rat   351 QSSKIKKGSKGDCTVLK------PTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIG-----Y 404

  Fly   356 HYMVSQGKSSGGFRYKIAKSLIMSKVKQALGFDRVLTLASAAAPMSPETKKYF-LSLDLKIVDAF 419
            .|.:.|.|.  |:...:...::..|||..|| ..|..:.|..||:||:|.::. :.....|...:
  Rat   405 DYKLEQIKK--GYDAPLCNLILFKKVKALLG-GNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGY 466

  Fly   420 GMSETAGCHTICLPDSVGLNTIGKTLPGCESKF---------INKDANGHGELCIRGRHVFMGYI 475
            |::|:.|..|:..........:|..|..||.|.         ::...|..||:.|.|:::.|||.
  Rat   467 GLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYF 531

  Fly   476 DNKEKTEE--SLDDD--CWLHSGDLGFVDDKGYVSLTGRSKEIIITAGGENIPPVHIENTIKKEL 536
            .|:|||.|  |:|::  .|..:||:|.....|.:.:..|.|:::....||.:....:|..: |..
  Rat   532 KNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAAL-KNC 595

  Fly   537 DAISN-------------AFLVGEQRKYLTVLITLKTEVDKDSGEPLDELSHESSVWVKSLGVEH 588
            ..|.|             :|:|..|:| ||:|...|                         |||.
  Rat   596 PLIDNICAFAKSDQSYVISFVVPNQKK-LTLLAQQK-------------------------GVEG 634

  Fly   589 KTVSDILAAGPC--PKVWKSIEDAIKRANKQSISNAQKVQKFTI------LPHDFSIPTGELGPT 645
            ..|.  :...|.  .::.|.|.:|         :||.|:::|.|      .|..::..||.:...
  Rat   635 SWVD--ICNNPAMEAEILKEIREA---------ANAMKLERFEIPIKVRLSPEPWTPETGLVTDA 688

  Fly   646 LKVKRNVVSKMYADEIEKLY 665
            .|:||..:...|..:||::|
  Rat   689 FKLKRKELKNHYLKDIERMY 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bgm	NP_001285923.1	FAA1	32..666	CDD:223953	166/716 (23%)
bgm	NP_001285923.1	ACSBG_like	69..665	CDD:213299	157/660 (24%)
Acsl4	XP_006257376.1	LC_FACS_euk1	121..696	CDD:341294	151/638 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810