DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rgl and 1700018F24Rik

DIOPT Version :9

Sequence 1:	NP_001261814.1	Gene:	Rgl / 44115	FlyBaseID:	FBgn0026376	Length:	973	Species:	Drosophila melanogaster
Sequence 2:	NP_081345.2	Gene:	1700018F24Rik / 69396	MGIID:	1916646	Length:	314	Species:	Mus musculus

Alignment Length:	197	Identity:	38/197 - (19%)
Similarity:	70/197 - (35%)	Gaps:	55/197 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 KPTWRLW--GEEHEKNAIFTVYLKKVRYHRPTPTASNDSDDEISHLEWETVRVRFVKAATLARLV 251
            :|....|  .:.:.|...|...|.|..|               :..|:....:.::.||....
Mouse    30 RPLTHFWHASDRNPKEPDFPYNLPKFTY---------------NSFEFVEQMIAYIPAAVHYH-- 77

  Fly   252 EALATDDGELESTFINVFLSTYRTFSTPKQVLSLLTQRYDALHEKHLEELEQAQQNGQVMDPAYD 316
                      :...|::||:.|..:.:..:||.||.:.|                      |::.
Mouse    78 ----------DQLSISLFLAVYHRYCSTWEVLDLLMKTY----------------------PSFQ 110

  Fly   317 PHASIHEQHKKTLVSALHVWLDGFPEDWHED-NL---QQILAFATKRLKRSDLHIKVLNRLERLI 377
            |.....:..|..:.|.|..|||.|||.:.:. ||   :|::.:|.:.:..::...:....|.||.
Mouse   111 PDCKQDQLTKSAIFSFLAHWLDTFPEHFFDSPNLAVMRQLMDYAGRHMPSAEFDKESRELLSRLE 175

  Fly   378 KQ 379
            :|
Mouse   176 EQ 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgl	NP_001261814.1	REM	246..378	CDD:100121	27/135 (20%)
		RasGEF	454..719	CDD:214539
		RalGDS_RA	858..946	CDD:176351
1700018F24Rik	NP_081345.2	REM	63..176	CDD:100121	29/146 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3629
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810