Protein Alignment Rgl and CG5522

DIOPT Version :9

• Sequence 1: NP_001261814.1
• Gene: Rgl / 44115
• FlyBaseID: FBgn0026376
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: NP_725613.1
• Gene: CG5522 / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 440
• Identity: 117/440 - (26%)
• Similarity: 176/440 - (40%)
• Gaps: 97/440 - (22%)

  Fly   436 HGPIYRGPTHFLQAFRFPHVPVRHFAEQLTRMDTELFKRLIPHQCLGHTWARRDSG-GSETVVAT 499
            |..|.:.....|.|.|   ||....|.|:|.:|..:|.::.|.:.....|.::|.. .:..:||.
  Fly   149 HASIKQLDAVILSALR---VPADVLANQITLLDFPVFAQIQPDELSSCAWTKKDKHVNTPNIVAF 210

  Fly   500 INQFNAVLFRVVSSILIDRLKPQERALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSK 564
            ..:||...|..|..|| :..:|::||..|:.:|.:|::|..|.|..||.|||||:.|.|||||:|
  Fly   211 TKRFNHTSFWTVQEIL-NAEQPKQRAEIITHFIKVAKKLHELNNLHSLFAIISAMQSASIYRLTK 274

  Fly   565 IWEVLPKERMEVFTELANICSEDNNAWTLREVLKREGTAKNPDPGSDHSDRHLQKLILNLGTQTS 629
            .|..|.|:....|..|::|.|:.:|...||.                    :|:.|.|
  Fly   275 TWACLSKKDRNAFDRLSDIFSDQDNWANLRS--------------------YLESLRL------- 312

  Fly   630 HGTIPYLGTFLTDLTMIHTANPDYLTENKLINFDKKRKEFEVLAQIKLLQGAANTYNLQADALFD 694
             ..|||||.|||||..|..|:|.   :..|....::.|...:|..|...| .:|..:||......
  Fly   313 -PCIPYLGLFLTDLIYIDLAHPH---KGGLEPEQRRNKMNNILRVISNYQ-QSNYKHLQKHEATQ 372

  Fly   695 HWFNSMPVFD------EREAFELSCRLEPPPPA-PRKSVVST----------------NTSLTNT 736
            .:..|:...:      |.:.::.|..|||..|: |..|..|:                |.|...|
  Fly   373 KYLTSIRYIEELQNIFEEDQYKRSLNLEPASPSGPSSSSCSSKESFNVEVVTPALGCLNLSPAKT 437

  Fly   737 -----TASSTASIMGHRKTDSIHSNSSSGAGSQFYCE------------LNSSTSSR-------- 776
                 .||.|..:.||||..|:.:...|.:..:.:.|            :.:.::.|
  Fly   438 IGSMRMASGTKFVPGHRKCRSLGTKFRSSSLPRNFAEKCQCCIVMIAPGIGTISNKRCRCRRIFG 502

  Fly   777 ----HNSLDRDVHHQHASLMSASSSVSNLSLDSSNSGGRQSGKLTHSQSM 822
                ||..|...||.|..|..:.....:..||.|        .|.||.::
  Fly   503 KIATHNHSDGHPHHLHLELDPSQVQPRHHLLDDS--------VLEHSDAL 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rgl	NP_001261814.1	REM	246..378	CDD:100121
		RasGEF	454..719	CDD:214539	81/271 (30%)
		RalGDS_RA	858..946	CDD:176351
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	79/272 (29%)
		PH_RalGPS1_2	578..692	CDD:270120
		PH	578..685	CDD:278594

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467926
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23113
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940