DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rgl and LOC110438234

DIOPT Version :9

Sequence 1:	NP_001261814.1	Gene:	Rgl / 44115	FlyBaseID:	FBgn0026376	Length:	973	Species:	Drosophila melanogaster
Sequence 2:	XP_021324867.1	Gene:	LOC110438234 / 110438234	-ID:	-	Length:	264	Species:	Danio rerio

Alignment Length:	182	Identity:	60/182 - (32%)
Similarity:	91/182 - (50%)	Gaps:	22/182 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 GEEHEKNAIFTVYLKKVRYHRPTPTASNDSDDEISHLEWETVRVRFVKAATLARLVEALATDDGE 260
            |||.|:.|:|::.::||:.::     |:.|..:..|.:..|.::|.:||.||.||||.:.|....
Zfish    16 GEEVEEGAVFSITVRKVQVYQ-----SSSSRGQQQHSDSHTCKLRSIKAGTLERLVENMLTAFRG 75

  Fly   261 LESTFINVFLSTYRTFSTPKQVLSLLTQRYDALHEKHLEELEQAQQNGQVMDPAYDPHASIHEQH 325
            .:||::.:||.|||||:|.||||.||..||..|         |.|....|.....|....:
Zfish    76 NDSTYVTIFLCTYRTFATTKQVLDLLLNRYAKL---------QQQPGPDVRRMTSDERTEL---- 127

  Fly   326 KKTLVSALHVWLDGFPED-WHEDN---LQQILAFATKRLKRSDLHIKVLNRL 373
            :.|:.|.|..|||.:.|| |....   |::::.:.......|||..:..|.|
Zfish   128 RNTISSILGAWLDQYSEDFWKPPEYSCLRRLILYLQINFPGSDLERRACNLL 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgl	NP_001261814.1	REM	246..378	CDD:100121	45/132 (34%)
		RasGEF	454..719	CDD:214539
		RalGDS_RA	858..946	CDD:176351
LOC110438234	XP_021324867.1	RasGEFN	53..179	CDD:214571	47/138 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D116220at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010