DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rgl and LOC101884125

DIOPT Version :9

Sequence 1:	NP_001261814.1	Gene:	Rgl / 44115	FlyBaseID:	FBgn0026376	Length:	973	Species:	Drosophila melanogaster
Sequence 2:	XP_021327881.1	Gene:	LOC101884125 / 101884125	-ID:	-	Length:	339	Species:	Danio rerio

Alignment Length:	411	Identity:	121/411 - (29%)
Similarity:	190/411 - (46%)	Gaps:	95/411 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 WRL-------WGEEHEKNAIFTVYLKKVRYHRPTPTASNDSDDEISHLEWETVRVRFVKAATLAR 249
            |.|       ||||||..|:|.|.|::    .|...::..::   :.:.:.|.:||.:|||||.:
Zfish     4 WELTMEPVQEWGEEHEDGAVFGVTLRR----EPVQQSAEPTE---AFVHYRTCKVRRLKAATLDK 61

  Fly   250 LVEALATDDGELESTFINVFLSTYRTFSTPKQVLSLLTQRYDALHEKHLEELEQAQQNGQVMDPA 314
            ||..| .|....|..:..:.|||||:|::..:::..|.||      |:|         ..|:|..
Zfish    62 LVSHL-LDPCCQEQDYSCIMLSTYRSFTSTNKLIETLFQR------KNL---------ASVLDSI 110

  Fly   315 YDPHASIHEQHKKTLVSALHVWLDGFPEDWHEDNLQQILAFATKRLKRSDLHIKVLNRLERLIKQ 379
            ..|::        .|.:.|.:|||.:.||:.:..:...|.....:|:.......:..:.|.|:|:
Zfish   111 NYPNS--------CLWTVLQLWLDEYSEDFRDSPMHSSLRLMCLKLRGHPSLFPLAKQYEALLKR 167

  Fly   380 SLYGNGGGSGGSENNGHSWLSAARSQQMQQFMIPTHYGSSYDLTDQFNGMYLSPMGHGPIYRGPT 444
            .                         |.:..:...    |.|||::.| :.:.
Zfish   168 F-------------------------QTEDVVAAV----SADLTEESN-LNME------------ 190

  Fly   445 HFLQAFRFPHV------PVRHFAEQLTRMDTELFKRLIPHQCLGHTWARRDSGG--SETVVATIN 501
              ::.|.|.::      .:...||||||:|.:||.:::|.||||..|::||...  |.:|.|||.
Zfish   191 --MRNFEFDNMEDFLDFSIMGVAEQLTRIDADLFVKVVPFQCLGCVWSQRDKNENLSPSVWATIT 253

  Fly   502 QFNAVLFRVVSSILIDRLK-PQERALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSKI 565
            |||||..||::|:|..... ..:||..|.:|:.:||..|.||||||||||:|||.||.:|||.|.
Zfish   254 QFNAVTNRVITSLLNSPTSTASQRARVIEKWVRVAQGCRELKNFSSLKAILSALQSNPVYRLRKT 318

  Fly   566 WEVLPKERMEVFTELANICSE 586
            |..:.:.|....|    :|.:
Zfish   319 WAAVSRYRQTTHT----LCRQ 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgl	NP_001261814.1	REM	246..378	CDD:100121	32/131 (24%)
		RasGEF	454..719	CDD:214539	61/142 (43%)
		RalGDS_RA	858..946	CDD:176351
LOC101884125	XP_021327881.1	RasGEF_N	53..148	CDD:306971	32/118 (27%)
LOC101884125	XP_021327881.1	RasGEF	202..>334	CDD:321950	60/135 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D116220at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010