Protein Alignment Rgl and LOC101884125

DIOPT Version :10

• Sequence 1: NP_001261814.1
• Gene: Rgl / 44115
• FlyBaseID: FBgn0026376
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: NP_001429808.1
• Gene: LOC101884125 / 101884125
• -ID: -
• Length: 711
• Species: Danio rerio
• Alignment Length: 782
• Identity: 246/782 - (31%)
• Similarity: 383/782 - (48%)
• Gaps: 126/782 - (16%)

  Fly   192 WRL-------WGEEHEKNAIFTVYLKKVRYHRPTPTASNDSDDEISHLEWETVRVRFVKAATLAR 249
            |.|       ||||||..|:|.|.|::    .|...::..::   :.:.:.|.:||.:|||||.:
Zfish     4 WELTMEPVQEWGEEHEDGAVFGVTLRR----EPVQQSAEPTE---AFVHYRTCKVRRLKAATLDK 61

  Fly   250 LVEALATDDGELESTFINVFLSTYRTFSTPKQVLSLLTQRYDALHEKHLEELEQAQQNGQVMDPA 314
            ||..| .|....|..:..:.|||||:|::..:::..|.||      |:|         ..|:|..
Zfish    62 LVSHL-LDPCCQEQDYSCIMLSTYRSFTSTNKLIETLFQR------KNL---------ASVLDSI 110

  Fly   315 YDPHASIHEQHKKTLVSALHVWLDGFPEDWHEDNLQQILAFATKRLKRSDLHIKVLNRLERLIKQ 379
            ..|::        .|.:.|.:|||.:.||:.:..:...|.....:|:.......:..:.|.|:|:
Zfish   111 NYPNS--------CLWTVLQLWLDEYSEDFRDSPMHSSLRLMCLKLRGHPSLFPLAKQYEALLKR 167

  Fly   380 SLYGNGGGSGGSENNGHSWLSAARSQQMQQFMIPTHYGSSYDLTDQFNGMYLSPMGHGPIYRGPT 444
            .                         |.:..:...    |.|||::.| :.:.
Zfish   168 F-------------------------QTEDVVAAV----SADLTEESN-LNME------------ 190

  Fly   445 HFLQAFRFPHV------PVRHFAEQLTRMDTELFKRLIPHQCLGHTWARRDSGG--SETVVATIN 501
              ::.|.|.::      .:...||||||:|.:||.:::|.||||..|::||...  |.:|.|||.
Zfish   191 --MRNFEFDNMEDFLDFSIMGVAEQLTRIDADLFVKVVPFQCLGCVWSQRDKNENLSPSVWATIT 253

  Fly   502 QFNAVLFRVVSSILIDRLK-PQERALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSKI 565
            |||||..||::|:|..... ..:||..|.:|:.:||..|.||||||||||:|||.||.:|||.|.
Zfish   254 QFNAVTNRVITSLLNSPTSTASQRARVIEKWVRVAQGCRELKNFSSLKAILSALQSNPVYRLRKT 318

  Fly   566 WEVLPKERMEVFTELANICSEDNNAWTLREVLKREGTAKNPDPGSDHSDRHLQKLILNLGTQTSH 630
            |..:.:|.:.||..|.....::|:..|.||:...:|:..:.|  |..:.:..::..|.....|:.
Zfish   319 WAAVSREAVSVFENLCETFPDENSVVTNREIFMEDGSQADED--SSTATKTSKRCPLTKPMNTAG 381

  Fly   631 GTIPYLGTFLTDLTMIHTANPDYLTENKLINFDKKRKEFEVLAQIKLLQGAANTYNLQADALFDH 695
            ||:|||||:||.|||:.||.|| ..|..||||:|:|:|:|:|.||:.||.:...|.|....|...
Zfish   382 GTVPYLGTYLTILTMLDTALPD-TVEGGLINFEKRRREYEILRQIRQLQASCAQYVLPHHTLVAA 445

  Fly   696 WFNSMPVFDEREAFELSCRLEPPPPAPRKSVVSTNTSLTNTTASSTASIMGHRKTDSIHSNSSSG 760
            |..|..:..::|::|||.:||.|......|...::..||...:|..:...|.||.....|.||||
Zfish   446 WLQSQKLLSDQESYELSRQLEFPQDTSPSSSGWSHRMLTKKLSSLLSGNEGSRKNADQISVSSSG 510

  Fly   761 AGSQFYCELNSSTSS----RHNSLDR-------DVHHQHASLMSASSSVSNLSLDSSNSGGRQSG 814
            :.|....:::|.:|:    .|:|..:       ..:...:|:||:||..|...|..|......|.
Zfish   511 SSSSETEDMSSQSSAFISPSHSSCGQSSTEAFPSSYTPDSSIMSSSSFSSQQDLSLSQPSPSSSS 575

  Fly   815 KLTHSQSMGNGLKSHGNGTTNGGSPHINAQLVQPSSGTPHSAPDFYIIRVTYETDNIELDGIVLY 879
            ..:..|.:.:..:|....|.    |..|.|:           .|..||||:.|..|   :| .:|
Zfish   576 ASSDPQHVSSHKRSFSMTTL----PFYNRQV-----------DDSCIIRVSVEFCN---NG-NMY 621

  Fly   880 KSIMLGNNERTPQVIRNAMLKLGLED-DPDRFTLAQVLPD-KELVMPKNANVYYAVNTNYNLNFI 942
            |||:|.:.::|.|||:.|:.|..||| |...|||.|:|.. :||::|:.|||:||::|:.|.:|:
Zfish   622 KSILLTSQDKTAQVIQRALQKHNLEDVDEQDFTLIQILAQGRELLIPEKANVFYAMSTSANYDFV 686

  Fly   943 LR 944
            ||
Zfish   687 LR 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rgl	NP_001261814.1	REM	246..378	CDD:100121	32/131 (24%)
		RasGEF	454..719	CDD:214539	112/273 (41%)
		RA_RalGDS_like	858..946	CDD:340449	41/89 (46%)
LOC101884125	NP_001429808.1	None