DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rgl and rgl3b

DIOPT Version :9

Sequence 1:	NP_001261814.1	Gene:	Rgl / 44115	FlyBaseID:	FBgn0026376	Length:	973	Species:	Drosophila melanogaster
Sequence 2:	XP_002667459.1	Gene:	rgl3b / 100329330	ZFINID:	ZDB-GENE-101130-2	Length:	230	Species:	Danio rerio

Alignment Length:	225	Identity:	72/225 - (32%)
Similarity:	111/225 - (49%)	Gaps:	32/225 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   733 LTNTTASSTASIMGHRKTDSIHSNSSSGAGSQFYCELNSSTSS----RHNSLDR-------DVHH 786
            ||...:|..:...|.||.....|.||||:.|....:::|.:|:    .|:|..:       ..:.
Zfish     2 LTKKLSSLLSGNEGSRKNADQISVSSSGSSSSETEDMSSQSSAFISPSHSSCGQSSTEAFPSSYT 66

  Fly   787 QHASLMSASSSVSNLSLDSSNSGGRQSGKLTHSQSMGNGLKSHGNGTTNGGSPHINAQLVQPSSG 851
            ..:|:||:||..|...|..|......|...:..|.:.:..:|....|.    |..|.|:
Zfish    67 PDSSIMSSSSFSSQQDLSLSQPSPSSSSASSDPQHVSSHKRSFSMTTL----PFYNRQV------ 121

  Fly   852 TPHSAPDFYIIRVTYETDNIELDGIVLYKSIMLGNNERTPQVIRNAMLKLGLED-DPDRFTLAQV 915
                 .|..||||:.|..|   :| .:||||:|.:.::|.|||:.|:.|..||| |...|||.|:
Zfish   122 -----DDSCIIRVSVEFCN---NG-NMYKSILLTSQDKTAQVIQRALQKHNLEDVDEQDFTLIQI 177

  Fly   916 LPD-KELVMPKNANVYYAVNTNYNLNFILR 944
            |.. :||::|:.|||:||::|:.|.:|:||
Zfish   178 LAQGRELLIPEKANVFYAMSTSANYDFVLR 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgl	NP_001261814.1	REM	246..378	CDD:100121
		RasGEF	454..719	CDD:214539
		RalGDS_RA	858..946	CDD:176351	41/89 (46%)
rgl3b	XP_002667459.1	RalGDS_RA	123..208	CDD:176351	41/89 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D116220at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010