Protein Alignment Rgl and rapgefl1

DIOPT Version :9

• Sequence 1: NP_001261814.1
• Gene: Rgl / 44115
• FlyBaseID: FBgn0026376
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: XP_001921020.3
• Gene: rapgefl1 / 100149497
• ZFINID: ZDB-GENE-131121-404
• Length: 621
• Species: Danio rerio
• Alignment Length: 658
• Identity: 127/658 - (19%)
• Similarity: 233/658 - (35%)
• Gaps: 183/658 - (27%)

  Fly   124 RSASAKPRRNSSYHSYDDLDVSSAVLNAERKVVASLKYLCACTGATLRNLSKKTKDLHAKNYTYT 188
            ||.|......||..|   ||.:...|.|:.....:|..|.:..|....|.::...|    ::..|
Zfish    80 RSPSLSSDEQSSEAS---LDTNWTPLPADTPENLALALLDSVAGKRYANCTEILLD----DFMLT 137

  Fly   189 KPT------------------------WRLWGEEHEKNAIFTVYLKKVRYHRPTPTASNDSD--- 226
            .|.                        |..|.....|.|:.||..:.:..:|.......|..
Zfish   138 HPIFLAPDKFQQVLLQQFSSEGKQGEGWPGWDGAERKLAVLTVAFRYLDTYRDLLQEEGDRSNTF 202

  Fly   227 ---------DEISHLEWETVRVRFVKAATLARLVEALATDDGELESTFINVFLSTYRTFSTPKQV 282
                     ||::... |.|. ..:|......::.:.|.:|.|                |..|||
Zfish   203 PKELYLCAVDELNRFP-ELVE-DVLKLQRWTEILHSPAEEDKE----------------SRKKQV 249

  Fly   283 LSLLT--QRYDALHEKHLEELEQAQQNGQVMDPAYDP-HASIHEQHKKTLVSALHVWLDGFPEDW 344
            ..|..  :|.||.    |:..|..:.:.::....|.| |:.:      |:.|.|..
Zfish   250 RPLFRHFRRIDAC----LQPREAFRGSDEIFCRVYTPDHSYV------TIRSRLSC--------- 295

  Fly   345 HEDNLQQILAFATKRLKRSD---------LHIKVLNRLERLI----KQSLYGNGGGSGGSENNGH 396
               .:.:|||...::|:.|:         :.:.|.:..|:.:    .::::...|      .|.|
Zfish   296 ---RVGEILALVKEKLQYSEDQPTQPANLILVAVTSSGEKAVFRPSDEAVFTTLG------VNTH 351

  Fly   397 SWLSAARSQQMQQFMIPTHYGSSYDLTDQFNGMYLSPMGHGPIYRGPTHFLQAFRFPHVPVRHFA 461
              |.|....:::. :||        |.::   ::.:| |...:     |.:.|        ...|
Zfish   352 --LFACEPAELES-LIP--------LPEE---IHWTP-GDSKL-----HDMSA--------EEVA 388

  Fly   462 EQLTRMDTELFKRLIPHQCLGHTW----ARRDSGGSETVVATINQFNAVLFRVVSSILIDRLKPQ 522
            .||...|.|||..:...:.:.:.:    ||......|.:   :.:.:.|...|.:.||..:..|:
Zfish   389 NQLVVFDWELFSCVHEVEFVCYVFHGEQARWRPLNLELI---LQRCSEVQHWVATEILQCQSLPK 450

  Fly   523 ERALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSKIWEVLPKERMEVFTELANICSED 587
            ...| :.::|.||...:..::..|..|::..|::.::.||...||.||.:..:.|.:..:|....
Zfish   451 RIQL-LRKFIKIAALCKQQQDLLSFLALVLGLDNPAVSRLRLTWEGLPGKFRKQFQQFESIADPS 514

  Fly   588 NNAWTLREVLKREGTAKNPDPGSDHSDRHLQKLILNLGTQTSHGTIPYLGTFLTDLTMIHTANPD 652
            .|..:.|::|   .:.:.|                         .||:....|.|||.:|.:...
Zfish   515 RNHKSYRDLL---ASLRAP-------------------------LIPFTPLLLKDLTFLHESCKT 551

  Fly   653 YLTENKLINFDKKRKEFEVLAQIK-------LLQGAANTYNLQADALFDHWFNSMPVFDERE-AF 709
            :  ..:|:||:|..|..|::..|:       .::...:..:||..|    :...:.|.|.:. .|
Zfish   552 F--HGELVNFEKMHKVAEMVRSIRRYRSSQLAMEAEPSPSHLQTKA----YVRQLQVIDNQNLLF 610

  Fly   710 ELSCRLEP 717
            |:|.:|||
Zfish   611 EMSSKLEP 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rgl	NP_001261814.1	REM	246..378	CDD:100121	26/147 (18%)
		RasGEF	454..719	CDD:214539	59/276 (21%)
		RalGDS_RA	858..946	CDD:176351
rapgefl1	XP_001921020.3	RasGEF	379..619	CDD:214539	61/291 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3629
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900