DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rgl and Gm3409

DIOPT Version :9

Sequence 1:	NP_001261814.1	Gene:	Rgl / 44115	FlyBaseID:	FBgn0026376	Length:	973	Species:	Drosophila melanogaster
Sequence 2:	XP_006504843.1	Gene:	Gm3409 / 100041566	MGIID:	3781587	Length:	319	Species:	Mus musculus

Alignment Length:	172	Identity:	28/172 - (16%)
Similarity:	62/172 - (36%)	Gaps:	47/172 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 VYLKKVRYHRPTPTASNDSDDE---------ISHLEWETVRVRFVKAATLARLVEALATDDGELE 262
            ::.:...:..|...:.|:.:.:         ....|:....:.::.||...|            :
Mouse    33 IHFRHASHSEPKVCSQNEQEPDSLPKRPQFNYDSQEYVVQMIHYIPAAIQKR------------D 85

  Fly   263 STFINVFLSTYRTFSTPKQVLSLLTQRYDALHEKHLEELEQAQQNGQVMDPAYDPHASIHEQHKK 327
            ...|.:||..|||:::..:||.||.:.|                      .::.|.....:|.|:
Mouse    86 HICITIFLGVYRTYASTWEVLDLLMRTY----------------------ASFRPDCIKDQQTKR 128

  Fly   328 TLVSALHVWLDGFPEDWHEDN----LQQILAFATKRLKRSDL 365
            .:...|..|...:|:|::|..    ::|.:.:....:..||:
Mouse   129 AIFRFLFGWFKKYPQDFYESPDLAVVRQFIDYVKHNVPSSDV 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rgl	NP_001261814.1	REM	246..378	CDD:100121	23/124 (19%)
		RasGEF	454..719	CDD:214539
		RalGDS_RA	858..946	CDD:176351
Gm3409	XP_006504843.1	REM	89..186	CDD:100121	22/104 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3629
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810