DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment slpr and NP1

DIOPT Version :9

Sequence 1:NP_001188558.1 Gene:slpr / 44111 FlyBaseID:FBgn0030018 Length:1155 Species:Drosophila melanogaster
Sequence 2:NP_563832.2 Gene:NP1 / 837421 AraportID:AT1G09000 Length:666 Species:Arabidopsis thaliana


Alignment Length:555 Identity:131/555 - (23%)
Similarity:221/555 - (39%) Gaps:127/555 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   133 EVIGSGGFCKVHRGYY--DGEEVAIK----IAHQTGEDDMQRMRDNVLQEAKLFWALKHENIAAL 191
            ::||.|.|..|:.|..  .||.:|:|    .|:...::..|.....:.:|.||...|.|.||...
plant    73 QLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIVRY 137

  Fly   192 RG-VCLNTKLCLVMEYARGGSLNRILA--GKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLK 253
            .| |..:..|.:::|:..|||::.:|.  |..|..|:..:..|:..|:.||||.|   |:|||:|
plant   138 LGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHA---IMHRDIK 199

  Fly   254 SSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSAA----GTYAWMPPEVISVSTYSKFSD 314
            .:|:|:.        .:..:|:.|||.::::.....|:.|    ||..||.||||..:.:|..:|
plant   200 GANILVD--------NKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVILQTGHSFSAD 256

  Fly   315 VWSYGVLLWELITGETPY-KGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPG 378
            :||.|..:.|::||:.|: :.:..::..:.:.......|||.|........:..|.|..|:.||.
plant   257 IWSVGCTVIEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAKDFLLKCLQEVPNLRPT 321

  Fly   379 FKEILKQLESIACSKFTLTPQESFHYMQECWRKEIAGVLHDL---------REKEKRFQTIEE-- 432
            ..|:||.       .|.:...      :|....::..||::|         ..|.....|.::  
plant   322 ASELLKH-------PFVMGKH------KESASTDLGSVLNNLSTPLPLQINNTKSTPDSTCDDVG 373

  Fly   433 ELRN-------KEEQLLRVQNEQREKANLLKIREQNLRERERVLIERELVM-----LQPVPSKRK 485
            ::.|       ..:.:..:||:     ||.:..:....|.:..||:.|..:     :.....|..
plant   374 DMCNFGSLNYSLVDPVKSIQNK-----NLWQQNDNGGDEDDMCLIDDENFLTFDGEMSSTLEKDC 433

  Fly   486 HKKGKKN--KPLQISLPTGFRHTITAVRDKAEQPGSPSFSGLRIVALTDGHKGKTWG-----PST 543
            |.|...:  ..:.|:|.:.|          .|.||             :|.|..|..     || 
plant   434 HLKKSCDDISDMSIALKSKF----------DESPG-------------NGEKESTMSMECDQPS- 474

  Fly   544 MHQRERSLLPSQLSGGQPEWPA-----QTSTHSSFSKS----AP-----NLDKKQQQQNQQQVAS 594
            ..:.:..|..|::.....|..|     ||..:..|..|    :|     ||...:::...:....
plant   475 YSEDDDELTESKIKAFLDEKAADLKKLQTPLYEEFYNSLITFSPSCMESNLSNSKREDTARGFLK 539

  Fly   595 LTP---PPGLGILGG-------------SGGAGGT 613
            |.|   .|..|.|||             |.|:||:
plant   540 LPPKSRSPSRGPLGGSPSRATDATSCSKSPGSGGS 574

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slprNP_001188558.1 SH3_MLK 47..104 CDD:212809
TyrKc 129..386 CDD:197581 79/266 (30%)
STKc_MLK 134..389 CDD:270963 79/268 (29%)
NP1NP_563832.2 STKc_MAPKKK 68..331 CDD:270783 79/275 (29%)
S_TKc 69..331 CDD:214567 79/275 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 92 1.000 Inparanoid score I2253
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.960

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