DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slpr and CTR1

DIOPT Version :9

Sequence 1:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_195993.1	Gene:	CTR1 / 831748	AraportID:	AT5G03730	Length:	821	Species:	Arabidopsis thaliana

Alignment Length:	311	Identity:	108/311 - (34%)
Similarity:	159/311 - (51%)	Gaps:	22/311 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 KIGDKVGVFPKDFVTDEDPLQLNVSSAIG-DIQPHEIEYNELDIKEVIGSGGFCKVHRGYYDGEE 152
            :..:::...|.:......|:....:..:| |....:|.:.:|:|||.||:|.|..|||..:.|.:
plant   510 RASNQIEAAPMNAPPISQPVPNRANRELGLDGDDMDIPWCDLNIKEKIGAGSFGTVHRAEWHGSD 574

  Fly   153 VAIKIAHQTGEDDMQRMRDN-VLQEAKLFWALKHENIAALRG-VCLNTKLCLVMEYARGGSLNRI 215
            ||:||..   |.|....|.| .|:|..:...|:|.||....| |.....|.:|.||...|||.|:
plant   575 VAVKILM---EQDFHAERVNEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRL 636

  Fly   216 LAGKIPPDVL-----VNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKI 275
            |......:.|     ::.|..:|:|||||||..| .|:||||||.|:|:.        ::.|:|:
plant   637 LHKSGAREQLDERRRLSMAYDVAKGMNYLHNRNP-PIVHRDLKSPNLLVD--------KKYTVKV 692

  Fly   276 TDFGLAREMYNT--QRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPL 338
            .||||:|...:|  ...|||||..||.|||:.....::.|||:|:||:||||.|.:.|:...:|.
plant   693 CDFGLSRLKASTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNPA 757

  Fly   339 SVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESI 389
            .|...|......|.||:.......|:::.||..:|.|||.|..|:..|..:
plant   758 QVVAAVGFKCKRLEIPRNLNPQVAAIIEGCWTNEPWKRPSFATIMDLLRPL 808

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	1/14 (7%)
		TyrKc	129..386	CDD:197581	102/265 (38%)
		STKc_MLK	134..389	CDD:270963	99/263 (38%)
CTR1	NP_195993.1	EDR1	208..413	CDD:291079
		TyrKc	551..805	CDD:197581	102/265 (38%)
		STKc_MAP3K-like	557..805	CDD:270901	98/259 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1208
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44329
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910