DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slpr and AT4G18950

DIOPT Version :9

Sequence 1:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_567568.1	Gene:	AT4G18950 / 827630	AraportID:	AT4G18950	Length:	459	Species:	Arabidopsis thaliana

Alignment Length:	410	Identity:	112/410 - (27%)
Similarity:	180/410 - (43%)	Gaps:	78/410 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 TALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGWWTGKIGDKVGVFPKDFVTDEDPLQ---- 109
            |||:....||..::      :.::|...:||.....|.:....|.:      |..:.|.::
plant    78 TALHVAACQGLKDV------VELLLDRKAEVDPKDRWGSTPFADAI------FYKNIDVIKILEI 130

  Fly   110 ---------LNVSSAIGDIQPHEIEYNELDI---KEVIGSGGFCKVHRGYYDGEEVAIKIAHQ-- 160
                     ::|.:| .::..:||..:|||.   || |..|.:|   ...:.|.:||:|....
plant   131 HGAKHPMAPMHVKTA-REVPEYEINPSELDFTQSKE-ITKGTYC---MAMWRGIQVAVKKLDDEV 190

  Fly   161 -TGEDDMQRMRDNVLQEAKLFWALKHENIAALRG-VCLNTKLCLVMEYARGGSLNRIL--AGKIP 221
             :.:|.:::..|    |..|...|:|.||....| |..:..:.:|.||...|.|..:|  .|::.
plant   191 LSDDDQVRKFHD----ELALLQRLRHPNIVQFLGAVTQSNPMMIVTEYLPRGDLRELLKRKGQLK 251

  Fly   222 PDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAR---- 282
            |...|.:|:.|||||:|||......||||||:.||:|   ..:..|     ||:.|||:::
plant   252 PATAVRYALDIARGMSYLHEIKGDPIIHRDLEPSNIL---RDDSGH-----LKVADFGVSKLVTV 308

  Fly   283 ---EMYNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPY--KGFDPLSVAY 342
               :.:..|.:|.    .::.|||.:...|...:||:|:.:::.|:|.|..|:  |.....|.||
plant   309 KEDKPFTCQDISC----RYIAPEVFTSEEYDTKADVFSFALIVQEMIEGRMPFAEKEDSEASEAY 369

  Fly   343 GVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKFTLTPQESFHYM-- 405
            ......|.....|..|.....|::.||...|.|||.|:||:|:||||            .|:|
plant   370 AGKHRPLFKAPSKNYPHGLKTLIEECWHEKPAKRPTFREIIKRLESI------------LHHMGH 422

  Fly   406 QECWRKEIAGVLHDLREKEK 425
            :..||........:...|:|
plant   423 KRQWRMRPLTCFQNFEHKKK 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	11/54 (20%)
		TyrKc	129..386	CDD:197581	85/274 (31%)
		STKc_MLK	134..389	CDD:270963	83/269 (31%)
AT4G18950	NP_567568.1	ANK repeat	42..73	CDD:293786
		Ank_2	47..134	CDD:372319	12/67 (18%)
		ANK repeat	75..106	CDD:293786	8/33 (24%)
		ANK repeat	108..133	CDD:293786	4/30 (13%)
		STKc_MAP3K-like	176..413	CDD:270901	78/252 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44329
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910