DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slpr and AT2G43850

DIOPT Version :9

Sequence 1:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster
Sequence 2:	NP_181913.3	Gene:	AT2G43850 / 818989	AraportID:	AT2G43850	Length:	479	Species:	Arabidopsis thaliana

Alignment Length:	394	Identity:	106/394 - (26%)
Similarity:	168/394 - (42%)	Gaps:	81/394 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 DGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGW---------WTGKI--------- 90
            ||.  |||:....:|      ..|.:..:||..:.:.....|         :.|.:
plant   110 DGR--TALHIAACEG------HLGVVKALLSRRANIDARDRWGSTAAADAKYYGNLDVYNLLKAR 166

  Fly    91 GDKVGVFPKDFVTDEDPLQLNVSSAIGDIQPHEI---EYNELDIKEVIGSGGFCKVHRGYY---- 148
            |.||   ||   |.:.|:.::        .|.|:   |.|.|:: :|..|.|   :.:|.|
plant   167 GAKV---PK---TRKTPMTVS--------NPREVPEYELNPLEV-QVRKSDG---ISKGAYQVAK 213

  Fly   149 -DGEEVAIKIAHQTGEDDMQRMRDNVLQ-EAKLFWALKHENIAALRG-VCLNTKLCLVMEYARGG 210
             :|..|::||..:....|.:|:  |..: |..|...::|.|:....| |..|..:.:|:||...|
plant   214 WNGTRVSVKILDKDSYSDPERI--NAFRHELTLLEKVRHPNVIQFVGAVTQNIPMMIVVEYNPKG 276

  Fly   211 SLNRIL--AGKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTL 273
            .|:..|  .|::.|...:.:|:.|||||||||...|..|||.|||..|:|:....:        |
plant   277 DLSVYLQKKGRLSPSKALRFALDIARGMNYLHECKPDPIIHCDLKPKNILLDRGGQ--------L 333

  Fly   274 KITDFGLAREMYNTQRMSAAGTYA--------WMPPEVISVSTYSKFSDVWSYGVLLWELITGET 330
            ||:.||:.|....:|..:....:.        ::.|||.....:....|..|:||:|:|:..|..
plant   334 KISGFGMIRLSKISQDKAKVANHKAHIDLSNYYIAPEVYKDEIFDLRVDAHSFGVILYEITEGVP 398

  Fly   331 PYKGFDPLSVAYGVAVNTLTLPIPKT----CPETWGALMKSCWQTDPHKRPGFKEILKQLESIA- 390
            .:....|..||..:.:.. ..|:.||    .|.....|::.||..:...||.|.||:.:|:.|.
plant   399 VFHPRPPEEVARMMCLEG-KRPVFKTKSRSYPPDIKELIEKCWHPEAGIRPTFSEIIIRLDKIVA 462

  Fly   391 -CSK 393
             |||
plant   463 NCSK 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	14/74 (19%)
		TyrKc	129..386	CDD:197581	79/277 (29%)
		STKc_MLK	134..389	CDD:270963	79/275 (29%)
AT2G43850	NP_181913.3	Ank_2	82..170	CDD:372319	12/67 (18%)
		ANK repeat	82..108	CDD:293786
		ANK repeat	110..141	CDD:293786	9/38 (24%)
		ANK repeat	143..168	CDD:293786	2/24 (8%)
		PKc_like	204..457	CDD:389743	75/263 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44329
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910