Protein Alignment slpr and itk

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: XP_073777810.1
• Gene: itk / 798906
• ZFINID: ZDB-GENE-990415-261
• Length: 630
• Species: Danio rerio
• Alignment Length: 513
• Identity: 125/513 - (24%)
• Similarity: 187/513 - (36%)
• Gaps: 172/513 - (33%)

  Fly    17 QQLEQL------HHPQ----IPEIPIPDLEQVETQVGDGSLWTALYDYDAQGEDELTLRRGEIVV 71
            ||.|:|      ::|.    :|..|.|.....|.   :..:..||.::..:...:|.|::.|...
Zfish   147 QQTEKLATGCSEYYPNGAKPLPPTPDPSRRSSEP---EERIVVALRNFTPKEHTDLPLQKDEEYF 208

  Fly    72 VLSTDSEVSGDVGWWTGKIGD-KVGVFPKDFVTD---------------------EDPLQ----- 109
            ::.     ..:..|||.|..| .||..|..:||:                     ||.|.
Zfish   209 IVD-----CSEPNWWTVKDKDGNVGSVPCIYVTEKLSNNIEKFEWYNKDINRTEAEDLLMQENKD 268

  Fly   110 -------------------LNVSSAIGD-----------IQ-------------------PHEIE 125
                               ..||.:.|:           :|                   |..|.
Zfish   269 GGFMVRNSKHAGVYTVSIFTRVSGSNGEKCPQVKHYQIKVQSEGEKVLYYLAEKYLFPTIPELIR 333

  Fly   126 Y---------------------NELDIKEV-----------------IGSGGFCKVHRGYYDGEE 152
            |                     |...|||:                 :|||.|..|.:|.:...|
Zfish   334 YHQHNPAGLITRLRHCVSRNVPNSARIKELSSDKWEIHPDEVKLSVELGSGQFGLVWKGSWQDME 398

  Fly   153 VAIKIAHQ--TGEDDMQRMRDNVLQEAKLFWALKHENIAALRGVCL-NTKLCLVMEYARGGSLNR 214
            ||:|...:  ..|::.:       :||::...|.|..:..|.||.. .:.:.||.|:...|.|..
Zfish   399 VAVKTVREGFMSEEEFK-------EEAQVMMKLSHNRLVQLYGVVTQRSPIYLVFEFMENGCLTE 456

  Fly   215 IL---AGKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKIT 276
            .|   .||:....|:...:.::.||.||.:.   :.|||||.:.|.|:.|        ...:||.
Zfish   457 FLRAKKGKLSQKALLEMCLDVSEGMAYLESS---NFIHRDLAARNCLVSE--------NSVVKIA 510

  Fly   277 DFGLAREMYNTQRMSAAGT---YAWMPPEVISVSTYSKFSDVWSYGVLLWELIT-GETPYKGFDP 337
            |||:.|.:.:.|..|:.|:   ..|..||||....||..|||||:||.:||:.: |.|||.....
Zfish   511 DFGMTRFVLDDQYTSSHGSKFPVRWSSPEVIKFGKYSSKSDVWSFGVFMWEVYSEGRTPYDNRSN 575

  Fly   338 LSVAYGVAVNTLT----LPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIAC 391
            ..|     |.||.    |..|:.||::...||:..|:..|..||.|..:|.:|   ||
Zfish   576 SEV-----VETLNAGHRLLKPRLCPQSVYELMQWSWKEKPEDRPSFALLLHEL---AC 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	14/57 (25%)
		STKc_MLK	134..389	CDD:270963	85/285 (30%)
itk	XP_073777810.1	None