Protein Alignment slpr and ptk6b

DIOPT Version :10

• Sequence 1: NP_001188558.1
• Gene: slpr / 44111
• FlyBaseID: FBgn0030018
• Length: 1155
• Species: Drosophila melanogaster
• Sequence 2: NP_001070140.1
• Gene: ptk6b / 767734
• ZFINID: ZDB-GENE-060929-1150
• Length: 511
• Species: Danio rerio
• Alignment Length: 474
• Identity: 120/474 - (25%)
• Similarity: 193/474 - (40%)
• Gaps: 139/474 - (29%)

  Fly    28 PEI--PIPDLEQVETQVGDGSLWTALYDYDAQGEDELTLRRGEIVVVLSTDSEVSGDVGWWTGKI 90
            |:|  |:|     .:...:.:::.||:|:.|:.:.||:.:.|:...:  ||.  |||  |||...
Zfish    54 PKIKPPLP-----PSANNNAAIYMALWDFKARNDQELSFKAGDKFEI--TDR--SGD--WWTANK 107

  Fly    91 GD-----KVGVFPKDF--------------------------------------VTDEDPL---- 108
            .|     ..|..|.::                                      |::.|.:
Zfish   108 KDIFGRVTTGFVPYNYLARDSVESQPWFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVL 172

  Fly   109 ------------------QLNVSS-------------------AIGD--------IQPH------ 122
                              |..|.:                   :|||        |:|.
Zfish   173 SVRTKENAKHFKIFQTGDQFYVDALFKFSSIVEVIEHYQSHPLSIGDLLSEPCIRIKPENVPPPS 237

  Fly   123 ----EIEYNELDIKEVIGSGGFCKVHRG-YYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFWA 182
                |:...|..::..:|||.|..|:.| :.:..:|||||..   .:|...:|:..| |.::...
Zfish   238 TDEWELPKEEFQLENQLGSGHFADVYSGKWKNHSKVAIKILK---NNDALVLREFQL-EVQIMKR 298

  Fly   183 LKHENIAALRGVCLNTK-LCLVMEYARGGSLNRILAG----KIPPDVLVNWAIQIARGMNYLHNE 242
            |:|:::.:|..||.::. ..::.|....|.|...|..    .:..:.|::.|.|:|.||.||  |
Zfish   299 LRHKHLISLFAVCTSSSPFYIITELIEKGDLLHFLRNPEGRSLQMESLIDMAAQVADGMAYL--E 361

  Fly   243 APMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMS--AAGTYAWMPPEVIS 305
            |..| |||||.:.|||:.:..        ..||.||||||.:.....:|  ....|.|..||.|.
Zfish   362 ANNS-IHRDLAARNVLVGDGY--------VCKIADFGLARIIKEPVYLSDDKKIPYKWTAPEAIG 417

  Fly   306 VSTYSKFSDVWSYGVLLWELIT-GETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCW 369
            ..|||..|||||:|:||:|::| |..||.|.:...|...:......:|.|..||:....:|::||
Zfish   418 HGTYSSKSDVWSFGILLYEIVTHGGIPYPGVNTGEVYDLITKENYRMPSPPKCPQAIYNIMRACW 482

  Fly   370 QTDPHKRPGFKEILKQLES 388
            :.:...||.||.:..:|::
Zfish   483 RIESVDRPNFKVLKDELDN 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809	19/99 (19%)
		STKc_MLK	134..389	CDD:270963	87/264 (33%)
ptk6b	NP_001070140.1	SH3_Brk	70..126	CDD:212781	18/61 (30%)
		SH2	132..216	CDD:214585	4/83 (5%)
		PTKc_Srm_Brk	241..502	CDD:133248	89/276 (32%)